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Journal Articles

Crystal Structures of DNA-bound Fish IRF10 and IRF11 Reveal the Determinants of IFN Regulation

Zhao-Xi Wang, Bin Liu, Haizhou Xie, Xin Liu, Xiangliang Li, Fuqiang Shi, Songying Ouyang, Yong-An Zhang
Journal: The Journal of Immunology
J Immunol (2024) 213 (5): 743–752.
https://doi.org/10.4049/jimmunol.2300414
Published: 26 July 2024
View article titled, Crystal Structures of DNA-bound Fish IRF10 and IRF11 Reveal the Determinants of IFN Regulation
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Includes: Supplementary data
Journal Articles

Unconventional IFNω-like Genes Dominate the Type I IFN Locus and the Constitutive Antiviral Responses in Bats

Rong Geng, Qi Wang, Yu-Lin Yao, Xu-Rui Shen, Jing-Kun Jia, Xi Wang, Yan Zhu, Qian Li, Zheng-Li Shi, Peng Zhou
Journal: The Journal of Immunology
J Immunol (2024) 213 (2): 204–213.
https://doi.org/10.4049/jimmunol.2300301
Published: 10 June 2024
View article titled, Unconventional <em>IFNω</em>-like Genes Dominate the Type I IFN Locus and the Constitutive Antiviral Responses in Bats
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Includes: Supplementary data
Journal Articles

Uncovering alterations in the murine interferon response due to dsRNA mycovirus during Aspergillus fumigatus infection

Alexander Rapp, Xi Wang, Brandon Ross, Christopher Tanner, Alayna Caffrey-Carr, Robert Cramer, Joshua J Obar, Andrew Olive, Sean Thomas
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 71.21.
https://doi.org/10.4049/jimmunol.210.Supp.71.21
Published: 01 May 2023
View article titled, Uncovering alterations in the murine interferon response due to dsRNA mycovirus during Aspergillus fumigatus infection
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Journal Articles

MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus

Xi Wang, Cristina Cunha, Madeleine S. Grau, Shelly J. Robertson, João F. Lacerda, António Campos, Jr., Katrien Lagrou, Johan Maertens, Sonja M. Best, Agostinho Carvalho, Joshua J. Obar
Journal: The Journal of Immunology
J Immunol (2022) 209 (2): 346–353.
https://doi.org/10.4049/jimmunol.2100759
Published: 15 July 2022
View article titled, MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against <em>Aspergillus fumigatus</em>
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Includes: Supplementary data
Journal Articles

Influenza-induced cytokine response predisposes hosts to secondary Aspergillus fumigatus infections

Madeleine S. Grau, Xi Wang, Joshua J. Obar
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 58.33.
https://doi.org/10.4049/jimmunol.208.Supp.58.33
Published: 01 May 2022
View article titled, Influenza-induced cytokine response predisposes hosts to secondary <em>Aspergillus fumigatus</em> infections
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Journal Articles

Enhanced Calcium Signal Induces NK Cell Degranulation but Inhibits Its Cytotoxic Activity

Yang Li, Minghang Yu, Jie Yin, Han Yan, Xi Wang
Journal: The Journal of Immunology
J Immunol (2022) 208 (2): 347–357.
https://doi.org/10.4049/jimmunol.2001141
Published: 15 January 2022
View article titled, Enhanced Calcium Signal Induces NK Cell Degranulation but Inhibits Its Cytotoxic Activity
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Includes: Supplementary data
Journal Articles

MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus

Xi Wang, Alayna K. Caffrey-Carr, Ko-wei Liu, Vanessa Espinosa, Walburga Croteau, Sourabh Dhingra, Amariliz Rivera, Robert A. Cramer, Joshua J. Obar
Journal: The Journal of Immunology
J Immunol (2020) 205 (11): 3058–3070.
https://doi.org/10.4049/jimmunol.2000802
Published: 01 December 2020
View article titled, MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against <em>Aspergillus fumigatus</em>
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Includes: Supplementary data
Journal Articles

Mda5/MAVS are essential for host resistance against Aspergillus fumigatus

Xi Wang, Alayna Katherine Caffrey, Vanessa Espinosa, Cristina Cunha, Walburga Croteau, João Lacerda, António Campos, Katrien Lagrou, Johan Maertens, Amariliz Rivera, Agostinho Carvohlo, Robert A Cramer, Joshua J Obar
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 156.15.
https://doi.org/10.4049/jimmunol.204.Supp.156.15
Published: 01 May 2020
View article titled, Mda5/MAVS are essential for host resistance against <em>Aspergillus fumigatus</em>
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Journal Articles

The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination

Chang Liu, Shan Huang, Xuelin Wang, Mingjie Wen, Jiarui Zheng, Wenjuan Wang, Yanbin Fu, Shunli Tian, Long Li, Zexing Li, Xi Wang
Journal: The Journal of Immunology
J Immunol (2019) 202 (10): 2957–2970.
https://doi.org/10.4049/jimmunol.1800656
Published: 15 May 2019
View article titled, The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination
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Includes: Supplementary data
Journal Articles

Zebrafish NDRG1a Negatively Regulates IFN Induction by Promoting the Degradation of IRF7

Long-Feng Lu, Shun Li, Zhao-Xi Wang, Shu-Bo Liu, Dan-Dan Chen, Yong-An Zhang
Journal: The Journal of Immunology
J Immunol (2019) 202 (1): 119–130.
https://doi.org/10.4049/jimmunol.1800490
Published: 01 January 2019
View article titled, Zebrafish NDRG1a Negatively Regulates IFN Induction by Promoting the Degradation of IRF7
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Includes: Supplementary data
Journal Articles

Mda5/MAVS signaling is essential for resistance against Aspergillus fumigatus

Joshua J. Obar, Alayna Katherine Caffrey, Xi Wang, Vanessa Espinosa, Yi-Wei Tang, Tobias Hohl, Amariliz Rivera, Robert Cramer
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 52.23.
https://doi.org/10.4049/jimmunol.200.Supp.52.23
Published: 01 May 2018
View article titled, Mda5/MAVS signaling is essential for resistance against <em>Aspergillus fumigatus</em>
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Journal Articles

Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy

Lili Yang, Drake J. Smith, Levina J. Lin, Heesung Moon, Alexander T. Pham, Xi Wang, Siyuan Liu, Sunjong Ji, Valerie Rezek, Saki Shimizu, Marlene Ruiz, Jennifer Lam, Deanna M. Janzen, Sanaz Memarzadeh, Donald B. Kohn, Jerome A. Zack, Scott G. Kitchen, Dong Sung An
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 157.9.
https://doi.org/10.4049/jimmunol.198.Supp.157.9
Published: 01 May 2017
View article titled, Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy
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Journal Articles

Tumor-Unrelated CD4 T Cell Help Augments CD134 plus CD137 Dual Costimulation Tumor Therapy

Payal Mittal, Marie-Clare St. Rose, Xi Wang, Joseph M. Ryan, Jeffrey S. Wasser, Anthony T. Vella, Adam J. Adler
Journal: The Journal of Immunology
J Immunol (2015) 195 (12): 5816–5826.
https://doi.org/10.4049/jimmunol.1502032
Published: 15 December 2015
View article titled, Tumor-Unrelated CD4 T Cell Help Augments CD134 plus CD137 Dual Costimulation Tumor Therapy
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Includes: Supplementary data
Journal Articles

Optimizing the efficacy of dual-costimulation cancer therapy by engaging tumor-unrelated CD4 T cell help (TUM2P.1009)

Payal Mittal, Xi Wang, Dinesh Uthaya, Marie-Clare St. Rose, Anthony Vella, Adam Adler
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 69.6.
https://doi.org/10.4049/jimmunol.194.Supp.69.6
Published: 01 May 2015
View article titled, Optimizing the efficacy of dual-costimulation cancer therapy by engaging tumor-unrelated CD4 T cell help (TUM2P.1009)
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Journal Articles

IFN-γ Production by Memory Helper T Cells Is Required for CD40-Independent Alloantibody Responses

Victoria Gorbacheva, Ran Fan, Xi Wang, William M. Baldwin, III, Robert L. Fairchild, Anna Valujskikh
Journal: The Journal of Immunology
J Immunol (2015) 194 (3): 1347–1356.
https://doi.org/10.4049/jimmunol.1401573
Published: 01 February 2015
View article titled, IFN-γ Production by Memory Helper T Cells Is Required for CD40-Independent Alloantibody Responses
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Includes: Supplementary data
Journal Articles

miR-20b Suppresses Th17 Differentiation and the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting RORγt and STAT3

Endong Zhu, Xi Wang, Bin Zheng, Qian Wang, Jianlei Hao, Siming Chen, Qiang Zhao, Liqing Zhao, Zhenzhou Wu, Zhinan Yin
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5599–5609.
https://doi.org/10.4049/jimmunol.1303488
Published: 15 June 2014
View article titled, miR-20b Suppresses Th17 Differentiation and the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting RORγt and STAT3
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Includes: Supplementary data
Journal Articles

Posttransplant inflammation promotes memory T cell recovery following antibody-mediated lymphoablation (TRAN3P.900)

Kathy Ayasoufi, Xi Wang, Anna Valujskikh
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 202.39.
https://doi.org/10.4049/jimmunol.192.Supp.202.39
Published: 01 May 2014
View article titled, Posttransplant inflammation promotes memory T cell recovery following antibody-mediated lymphoablation (TRAN3P.900)
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Journal Articles

Targeting antigen-loss variant tumors through CD134 plus CD137 dual costimulation-mediated bystander programming (VAC10P.964)

Payal Mittal, Xi Wang, Marie-Clare St. Rose, Anthony Vella, Adam Adler
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 204.3.
https://doi.org/10.4049/jimmunol.192.Supp.204.3
Published: 01 May 2014
View article titled, Targeting antigen-loss variant tumors through CD134 plus CD137 dual costimulation-mediated bystander programming (VAC10P.964)
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Journal Articles

IL-12p35 single chain subunit antagonizes IL-6 mediated STAT1 and STAT3 activation and prevents expansion of Th17 cells in experimental autoimmune uveitis (CCR1P.246)

Ivy Dambuza, Cheng-Rong Yu, Ren-Xi Wang, Sung-Ye Kim, Rashid Mahdi, Monika Dolinska, Yuri Sergeev, Paul Wingfield, Charles Egwuagu
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 48.6.
https://doi.org/10.4049/jimmunol.192.Supp.48.6
Published: 01 May 2014
View article titled, IL-12p35 single chain subunit antagonizes IL-6 mediated STAT1 and STAT3 activation and prevents expansion of Th17 cells in experimental autoimmune uveitis (CCR1P.246)
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Journal Articles

B cells are required for CD8 T cell recovery after antibody-mediated depletion (TRAN3P.895)

Kathy Ayasoufi, Xi Wang, Anna Valujskikh
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 202.34.
https://doi.org/10.4049/jimmunol.192.Supp.202.34
Published: 01 May 2014
View article titled, B cells are required for CD8 T cell recovery after antibody-mediated depletion (TRAN3P.895)
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