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Journal Articles

IRF4 overexpression in therapeutic anti-tumor CD8 T cells inhibits tumor growth by driving functional state transition of therapeutic and endogenous CD8 T cells in tumors

hui yan, Hedong Zhang, Dawei Zou, Jinfei Fu, Xiaolong Zhang, Xiang Xiao, Yang Guo, Guohua Wang, Anze Yu, Xian C. Li, Wenhao Chen
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 165.15.
https://doi.org/10.4049/jimmunol.204.Supp.165.15
Published: 01 May 2020
View article titled, IRF4 overexpression in therapeutic anti-tumor CD8 T cells inhibits tumor growth by driving functional state transition of therapeutic and endogenous CD8 T cells in tumors
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Journal Articles

Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions

Yaling Dou, Junji Xing, Gangcheng Kong, Guangchuan Wang, Xiaohua Lou, Xiang Xiao, Eric Vivier, Xian C. Li, Zhiqiang Zhang
Journal: The Journal of Immunology
J Immunol (2019) 203 (4): 873–880.
https://doi.org/10.4049/jimmunol.1900171
Published: 15 August 2019
View article titled, Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions
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Includes: Supplementary data
Journal Articles

Role of the NF-κB Family Member RelB in Regulation of Foxp3+ Regulatory T Cells In Vivo

Junhui Li, Shuqiu Chen, Wenhao Chen, Qifa Ye, Yaling Dou, Yue Xiao, Lei Zhang, Laurie J. Minze, Xian C. Li, Xiang Xiao
Journal: The Journal of Immunology
J Immunol (2018) 200 (4): 1325–1334.
https://doi.org/10.4049/jimmunol.1701310
Published: 15 February 2018
View article titled, Role of the NF-κB Family Member RelB in Regulation of Foxp3<sup>+</sup> Regulatory T Cells In Vivo
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Includes: Supplementary data
Journal Articles

IRF4 controls a core regulatory circuit of T cell dysfunction in transplantation

Jie Wu, Xiaomin Shi, Xiang Xiao, Laurie Minze, Jin Wang, Rafik M. Ghobrial, Jiahong Xia, Roger Sciammas, Xian C. Li, Wenhao Chen
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 124.10.
https://doi.org/10.4049/jimmunol.198.Supp.124.10
Published: 01 May 2017
View article titled, IRF4 controls a core regulatory circuit of T cell dysfunction in transplantation
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Journal Articles

OX40 signaling activates epigenetic mechanisms to repress Th17 cells and Th17-related autoimmune diseases (LYM5P.708)

Xiang Xiao, Xiaomin Shi, Yihui Fan, xiaolong zhang, minhao wu, wentao liu, Picheng Zhao, chenglin wu, Laurie Minze, Rafik Ghobrial, Xian Li
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 134.13.
https://doi.org/10.4049/jimmunol.194.Supp.134.13
Published: 01 May 2015
View article titled, OX40 signaling activates epigenetic mechanisms to repress Th17 cells and Th17-related autoimmune diseases (LYM5P.708)
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Journal Articles

OX40 ligation recruits the E3 ubiquitin ligases TRAF6 and cIAP2 that cooperatively activate the non-canonical NF-κB pathway (IRM15P.608)

Yihui Fan, Xiang Xiao, Xiaomin Shi, Rafik Ghobrial, Laurie Minze, Xian Li
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 199.20.
https://doi.org/10.4049/jimmunol.194.Supp.199.20
Published: 01 May 2015
View article titled, OX40 ligation recruits the E3 ubiquitin ligases TRAF6 and cIAP2 that cooperatively activate the non-canonical NF-κB pathway (IRM15P.608)
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Journal Articles

GITR costimulation redirects regulatory T cells into Th9 cells to promote antitumor immunity (LYM8P.643)

Xiaomin Shi, Xiang Xiao, minhao wu, Yihui Fan, xiaolong zhang, chenglin wu, Rafik Ghobrial, Xian Li
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 201.19.
https://doi.org/10.4049/jimmunol.194.Supp.201.19
Published: 01 May 2015
View article titled, GITR costimulation redirects regulatory T cells into Th9 cells to promote antitumor immunity (LYM8P.643)
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Journal Articles

Innate NK Cells and Macrophages Recognize and Reject Allogeneic Nonself In Vivo via Different Mechanisms

Wentao Liu, Xiang Xiao, Gulcin Demirci, Joren Madsen, Xian C. Li
Journal: The Journal of Immunology
J Immunol (2012) 188 (6): 2703–2711.
https://doi.org/10.4049/jimmunol.1102997
Published: 15 March 2012
View article titled, Innate NK Cells and Macrophages Recognize and Reject Allogeneic Nonself In Vivo via Different Mechanisms
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Journal Articles

New Insights on OX40 in the Control of T Cell Immunity and Immune Tolerance In Vivo

Xiang Xiao, Weihua Gong, Gulcin Demirci, Wentao Liu, Silvia Spoerl, Xiufeng Chu, D. Keith Bishop, Laurence A. Turka, Xian C. Li
Journal: The Journal of Immunology
J Immunol (2012) 188 (2): 892–901.
https://doi.org/10.4049/jimmunol.1101373
Published: 15 January 2012
View article titled, New Insights on OX40 in the Control of T Cell Immunity and Immune Tolerance In Vivo
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Journal Articles

OX40/OX40L Costimulation Affects Induction of Foxp3+ Regulatory T Cells in Part by Expanding Memory T Cells In Vivo

Xiang Xiao, Alexander Kroemer, Wenda Gao, Naoto Ishii, Gulcin Demirci, Xian Chang Li
Journal: The Journal of Immunology
J Immunol (2008) 181 (5): 3193–3201.
https://doi.org/10.4049/jimmunol.181.5.3193
Published: 01 September 2008
View article titled, OX40/OX40L Costimulation Affects Induction of Foxp3<sup>+</sup> Regulatory T Cells in Part by Expanding Memory T Cells In Vivo
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Journal Articles

The Innate NK Cells, Allograft Rejection, and a Key Role for IL-15

Alexander Kroemer, Xiang Xiao, Nicolas Degauque, Karoline Edtinger, Haiming Wei, Gulcin Demirci, Xian Chang Li
Journal: The Journal of Immunology
J Immunol (2008) 180 (12): 7818–7826.
https://doi.org/10.4049/jimmunol.180.12.7818
Published: 15 June 2008
View article titled, The Innate NK Cells, Allograft Rejection, and a Key Role for IL-15
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Journal Articles

OX40 Controls Functionally Different T Cell Subsets and Their Resistance to Depletion Therapy

Alexander Kroemer, Xiang Xiao, Minh Diem Vu, Wenda Gao, Keisuke Minamimura, Ming Chen, Takashi Maki, Xian Chang Li
Journal: The Journal of Immunology
J Immunol (2007) 179 (8): 5584–5591.
https://doi.org/10.4049/jimmunol.179.8.5584
Published: 15 October 2007
View article titled, OX40 Controls Functionally Different T Cell Subsets and Their Resistance to Depletion Therapy
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