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Journal Articles

A distinct autoimmune signature in Post-treatment Lyme Disease Syndrome (PTLD)

Xin Chen, Xin Zhou, Haozhen Wang, Xuhuai Ji, Alison Rebman, Mark Soloski, Christine Wagner, Michael Snyder, William Robinson, John Aucott, Mark Davis
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 1119_5718.
https://doi.org/10.4049/jimmunol.212.supp.1119.5718
Published: 01 May 2024
View article titled, A distinct autoimmune signature in Post-treatment Lyme Disease Syndrome (PTLD)
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Journal Articles

Epigenetic Regulation of IL-23 by E3 Ligase FBXW7 in Dendritic Cells Is Critical for Psoriasis-like Inflammation

Yinjing Song, Xiangtong Zhao, Hao Qu, Yixin Su, Rukun He, Luxia Chen, Lutong Fang, Jiaying Li, Ziqi Zou, Jia He, Zilong Li, Yaohan Xu, Xin Chen, Hao Cheng, Yong Xu, Qingqing Wang, Lihua Lai
Journal: The Journal of Immunology
J Immunol (2023) 211 (11): 1701–1713.
https://doi.org/10.4049/jimmunol.2300023
Published: 16 October 2023
View article titled, Epigenetic Regulation of IL-23 by E3 Ligase FBXW7 in Dendritic Cells Is Critical for Psoriasis-like Inflammation
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Includes: Supplementary data
Journal Articles

Single-cell sequencing of PBMC characterizes a distinct inflammatory monocyte subset in Lyme disease patients with Post-Treatment Lyme Disease Syndrome (PTLD)

Xin Chen, Xin Zhou, Xuhuai Ji, Molly Miranda, Alison Rebman, Karan Kathuria, William H Robinson, John Aucott, Mark M Davis
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 155.18.
https://doi.org/10.4049/jimmunol.210.Supp.155.18
Published: 01 May 2023
View article titled, Single-cell sequencing of PBMC characterizes a distinct inflammatory monocyte subset in Lyme disease patients with Post-Treatment Lyme Disease Syndrome (PTLD)
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Journal Articles

Distinct roles of CD4 +and CD8 +Tregs in regulating human autoreactive T cells, B cells, and antibodies in genetically engineered tonsil organoid system

Xin Chen, Venkata Mallajosyula, Mustafa Ghanizada, Elsa Sola, Lei Chen, Lilit Kamalyan, Jing Li, Mark M Davis
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 247.20.
https://doi.org/10.4049/jimmunol.210.Supp.247.20
Published: 01 May 2023
View article titled, Distinct roles of CD4 <sup>+</sup>and CD8 <sup>+</sup>Tregs in regulating human autoreactive T cells, B cells, and antibodies in genetically engineered tonsil organoid system
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Journal Articles

TNFR2-targeting peptide for cancer immunotherapy

Xin Chen, Ping Liao, Zhonghao Chen
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 252.24.
https://doi.org/10.4049/jimmunol.210.Supp.252.24
Published: 01 May 2023
View article titled, TNFR2-targeting peptide for cancer immunotherapy
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Journal Articles

Engineering Human MAIT Cells with Chimeric Antigen Receptors for Cancer Immunotherapy

Mikail Dogan, Ece Karhan, Lina Kozhaya, Lindsey Placek, Xin Chen, Mesut Yigit, Derya Unutmaz
Journal: The Journal of Immunology
J Immunol (2022) 209 (8): 1523–1531.
https://doi.org/10.4049/jimmunol.2100856
Published: 15 October 2022
View article titled, Engineering Human MAIT Cells with Chimeric Antigen Receptors for Cancer Immunotherapy
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Includes: Supplementary data
Journal Articles

Developing a model of autoimmune diseases with human tonsil organoids

Xin Chen, Mustafa Ghanizada, Elsa Sola, Mark M Davis
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 44.12.
https://doi.org/10.4049/jimmunol.208.Supp.44.12
Published: 01 May 2022
View article titled, Developing a model of autoimmune diseases with human tonsil organoids
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Journal Articles

Inhibition of Aurora-A recruited CD8+ T cells infiltration via mediating IL-10 production of cancer cells

Jing Yang, Jing Han, Zhen Jiang, Chennan Wang, Xin Chen, Rongqing Li, Na Sun, Xiangye Liu, Kuiyang Zheng, Takayuki Ikezoe
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 241.13.
https://doi.org/10.4049/jimmunol.204.Supp.241.13
Published: 01 May 2020
View article titled, Inhibition of Aurora-A recruited CD8<sup>+</sup> T cells infiltration via mediating IL-10 production of cancer cells
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Journal Articles

JAK2V617F expressing macrophages stimulate IL-6 production through PKM1 mediated STAT3 activation

Takayuki Ikezoe, Rongqing Li, Na Sun, Xin Chen, Jing Yang
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 59.18.
https://doi.org/10.4049/jimmunol.204.Supp.59.18
Published: 01 May 2020
View article titled, JAK2<sup>V617F</sup> expressing macrophages stimulate IL-6 production through PKM1 mediated STAT3 activation
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Journal Articles

Porcine Reproductive and Respiratory Syndrome Virus Enhances Self-Replication via AP-1–Dependent Induction of SOCS1

Xuegang Luo, Xin-xin Chen, Songlin Qiao, Rui Li, Sha Xie, Xinyu Zhou, Ruiguang Deng, En-min Zhou, Gaiping Zhang
Journal: The Journal of Immunology
J Immunol (2020) 204 (2): 394–407.
https://doi.org/10.4049/jimmunol.1900731
Published: 15 January 2020
View article titled, Porcine Reproductive and Respiratory Syndrome Virus Enhances Self-Replication via AP-1–Dependent Induction of SOCS1
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Includes: Supplementary data
Journal Articles

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing

Xin Chen, Lina Kozhaya, Cihan Tastan, Lindsey Placek, Mikail Dogan, Meghan Horne, Rebecca Abblett, Ece Karhan, Martin Vaeth, Stefan Feske, Derya Unutmaz
Journal: The Journal of Immunology
J Immunol (2018) 201 (5): 1586–1598.
https://doi.org/10.4049/jimmunol.1701616
Published: 01 September 2018
View article titled, Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing
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Includes: Supplementary data
Journal Articles

Tumor necrosis factor receptor II (TNFR2) promotes the growth of mouse CT26 colon cancer

Xin Chen, Ping Li, Xinyu Yang, Xiaosu Miao, Hua Luo
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 178.7.
https://doi.org/10.4049/jimmunol.200.Supp.178.7
Published: 01 May 2018
View article titled, Tumor necrosis factor receptor II (TNFR2) promotes the growth of mouse CT26 colon cancer
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Journal Articles

Tetrandrine (TET) up-regulated mTNF expression on dendritic cells and consequently induces TNFR2 mediated proliferation of Tregs

Tianzhen He, De Yang, Xin Chen, Joost J. Oppenheim
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 47.19.
https://doi.org/10.4049/jimmunol.200.Supp.47.19
Published: 01 May 2018
View article titled, Tetrandrine (TET) up-regulated mTNF expression on dendritic cells and consequently induces TNFR2 mediated proliferation of Tregs
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Journal Articles

α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells

Xi-He Zhang, Xiao-Dong Lian, Zheng-Xi Dai, Hong-Yi Zheng, Xin Chen, Yong-Tang Zheng
Journal: The Journal of Immunology
J Immunol (2017) 199 (6): 2030–2042.
https://doi.org/10.4049/jimmunol.1602183
Published: 15 September 2017
View article titled, α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells
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Includes: Supplementary data
Journal Articles

The p38 MAPK inhibitor SB203580 abrogates TNF-mediated expansion of regulatory T cells

Xin Chen, Tianzhen He
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 141.16.
https://doi.org/10.4049/jimmunol.198.Supp.141.16
Published: 01 May 2017
View article titled, The p38 MAPK inhibitor SB203580 abrogates TNF-mediated expansion of regulatory T cells
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Journal Articles

Development of a curative therapeutic vaccine (TheraVac) for the treatment of large established tumors

De Yang, Yingjie Nie, Anna L Trivett, Zhen Han, Xin Chen, Joost J Oppenheim
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 79.20.
https://doi.org/10.4049/jimmunol.198.Supp.79.20
Published: 01 May 2017
View article titled, Development of a curative therapeutic vaccine (TheraVac) for the treatment of large established tumors
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Journal Articles

Tetrandrine (TET), an immunosuppressive component of Chinese herb, induces tolerogenic dendritic cells and consequently expands regulatory T cells

Xin Chen, Joost J Oppenheim
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 70.8.
https://doi.org/10.4049/jimmunol.196.Supp.70.8
Published: 01 May 2016
View article titled, Tetrandrine (TET), an immunosuppressive component of Chinese herb, induces tolerogenic dendritic cells and consequently expands regulatory T cells
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Journal Articles

Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers

Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, Xin Chen, Robert Wersto, Ranjan Sen, Howard A. Young, Michael Croft, Luigi Ferrucci, Arya Biragyn
Journal: The Journal of Immunology
J Immunol (2016) 196 (8): 3385–3397.
https://doi.org/10.4049/jimmunol.1502034
Published: 15 April 2016
View article titled, Aging Converts Innate B1a Cells into Potent CD8<sup>+</sup> T Cell Inducers
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Includes: Supplementary data
Journal Articles

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

Jonathan M. Weiss, Jeff J. Subleski, Tim Back, Xin Chen, Stephanie K. Watkins, Hideo Yagita, Thomas J. Sayers, William J. Murphy, Robert H. Wiltrout
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5821–5829.
https://doi.org/10.4049/jimmunol.1400404
Published: 15 June 2014
View article titled, Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy
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Includes: Supplementary data
Journal Articles

TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis (CCR3P.204)

Xin Chen, Haitao Xiao, O.M.Zack Howard, Joost Oppenheim
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 115.1.
https://doi.org/10.4049/jimmunol.192.Supp.115.1
Published: 01 May 2014
View article titled, TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis (CCR3P.204)
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