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Journal Articles

Staphylococcus aureus Enterotoxin B Is a Cofactor of Food Allergy beyond a Superantigen

Jin Yuan, Ping Tong, Zhongliang Wang, Xiaoqian Xu, Xiaoli Zhao, Xuanyi Meng, Yong Wu, Xin Li, Jinyan Gao, Hongbing Chen
Journal: The Journal of Immunology
J Immunol (2023) 211 (9): 1287–1297.
https://doi.org/10.4049/jimmunol.2200549
Published: 13 September 2023
View article titled, <em>Staphylococcus aureus</em> Enterotoxin B Is a Cofactor of Food Allergy beyond a Superantigen
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Includes: Supplementary data
Journal Articles

Genome-Wide CRISPR/Cas9 Screening Identifies That Mitochondrial Solute Carrier SLC25A23 Attenuates Type I IFN Antiviral Immunity via Interfering with MAVS Aggregation

Hongguang Zhang, Xin Li, Yiwei Wang, Xianxian Liu, Jing Guo, Zheng Wang, Lulu Zhang, Sidong Xiong, Chunsheng Dong
Journal: The Journal of Immunology
J Immunol (2023) 211 (9): 1406–1417.
https://doi.org/10.4049/jimmunol.2300187
Published: 11 September 2023
View article titled, Genome-Wide CRISPR/Cas9 Screening Identifies That Mitochondrial Solute Carrier SLC25A23 Attenuates Type I IFN Antiviral Immunity via Interfering with MAVS Aggregation
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Includes: Supplementary data
Journal Articles

B cell Tet2 promotes maturation of the antibody response through active DNA demethylation and OGT-mediated histone glycosylation of Aicdaand Prdm1loci

Shili Li, Yibo Peng, Xin Li, Zhimin Yang, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 149.10.
https://doi.org/10.4049/jimmunol.210.Supp.149.10
Published: 01 May 2023
View article titled, B cell Tet2 promotes maturation of the antibody response through active DNA demethylation and OGT-mediated histone glycosylation of <em>Aicda</em>and <em>Prdm1</em>loci
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Journal Articles

A CCL5 chemokine trail laid down by migratory dendritic cells directs CCR5 +antigen-presenting monocytes into draining lymph nodes

Kavita Rawat, Anita Tewari, Xin Li, Arlind B Mara, William T King, Sophie L Gibbings, Chinaza F Nnam, Fred B Kolling, Bart N Lambrecht, Claudia V Jakubzick
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 221.01.
https://doi.org/10.4049/jimmunol.210.Supp.221.01
Published: 01 May 2023
View article titled, A CCL5 chemokine trail laid down by migratory dendritic cells directs CCR5 <sup>+</sup>antigen-presenting monocytes into draining lymph nodes
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Journal Articles

RenMice™ HiTS platform enables identification of novel therapeutic antibodies

Jenna Frame, Xiaoqian Zhang, James Jin, Rebecca Soto, Shujin Zhang, Xin Li, Jing Zhang, Yuelei Shen
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 116.15.
https://doi.org/10.4049/jimmunol.208.Supp.116.15
Published: 01 May 2022
View article titled, RenMice™ HiTS platform enables identification of novel therapeutic antibodies
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Journal Articles

Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats

Pengyan Wang, Can Yue, Kefang Liu, Dan Lu, Sai Liu, Sijia Yao, Xin Li, Xiaoling Su, Keyi Ren, Yan Chai, Jianxun Qi, Yingze Zhao, Yongliang Lou, Zeyu Sun, George F. Gao, William J. Liu
Journal: The Journal of Immunology
J Immunol (2021) 207 (8): 2167–2178.
https://doi.org/10.4049/jimmunol.2100350
Published: 15 October 2021
View article titled, Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats
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Includes: Supplementary data
Journal Articles

Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites

Hao Guo, Wei-Chun Chou, Yunjia Lai, Kaixin Liang, Jason Tam, W. June Brickey, Liang Chen, Nathan D. Montgomery, Xin Li, Lauren M. Bohannon, Anthony D. Sung, Nelson J. Chao, Jonathan U. Peled, Antonio L.C. Gomes, Marcel R.M. van den Brink, Matthew J. French, Andrew N. Macintyre, Gregory D. Sempowski, Xianming Tan, R. Balfour Sartor, Kun Lu, Jenny P.Y. Ting
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 99.02.
https://doi.org/10.4049/jimmunol.206.Supp.99.02
Published: 01 May 2021
View article titled, Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
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Journal Articles

A novel human milk protein-derived peptide BCCY-1 exerts immunomodulatory effects on monocytes through NF-κB and MAPK signaling pathways

Yan Cao, Jinyang Cai, Xin Li, Chenbo Ji
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 73.16.
https://doi.org/10.4049/jimmunol.204.Supp.73.16
Published: 01 May 2020
View article titled, A novel human milk protein-derived peptide BCCY-1 exerts immunomodulatory effects on monocytes through NF-κB and MAPK signaling pathways
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Journal Articles

Sensing Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

Xin Li, Irina Leonardi, Alexa Semon, Itai Doron, Iris H Gao, Gregory Garbe’s Putzel, Youngjun Kim, Hiroki Kabata, David Artis, William D Fiers, Amanda E Ramer-Tait, ILIYAN ILIEV
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 191.3.
https://doi.org/10.4049/jimmunol.202.Supp.191.3
Published: 01 May 2019
View article titled, Sensing Fungal Dysbiosis by Gut-Resident CX3CR1<sup>+</sup> Mononuclear Phagocytes Aggravates Allergic Airway Disease
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Journal Articles

Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity

Sahar Bagherzadeh Yazdchi, Mariko Witalis, Alexandre P. Meli, Joanne Leung, Xin Li, Vincent Panneton, Jinsam Chang, Joanna Li, Stephen L. Nutt, Randy L. Johnson, Dae-Sik Lim, Hua Gu, Irah L. King, Woong-Kyung Suh
Journal: The Journal of Immunology
J Immunol (2019) 202 (1): 69–78.
https://doi.org/10.4049/jimmunol.1701407
Published: 01 January 2019
View article titled, Hippo Pathway Kinase Mst1 Is Required for Long-Lived Humoral Immunity
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Includes: Supplementary data
Journal Articles

Induction of class-switched and somatically hypermutated primary and anamnestic antibody responses by TLR-BCR co-engagement in Tcrβ−/−Tcrδ−/−and NSG/B-cell mice

Carlos Eduardo Rivera, Xin Li, Hui Yan, Daniel Chupp, Julia Taylor, Hong Zan, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 107.12.
https://doi.org/10.4049/jimmunol.200.Supp.107.12
Published: 01 May 2018
View article titled, Induction of class-switched and somatically hypermutated primary and anamnestic antibody responses by TLR-BCR co-engagement in <em>Tcrβ</em><em><sup>−/−</sup></em><em>Tcrδ</em><em><sup>−/−</sup></em>and NSG/B-cell mice
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Journal Articles

Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome

Haipeng Yin, Qiang Guo, Xin Li, Tiantian Tang, Cuiling Li, Hengxiao Wang, Yuanxin Sun, Qi Feng, Chunhong Ma, Chengjiang Gao, Fan Yi, Jun Peng
Journal: The Journal of Immunology
J Immunol (2018) 200 (8): 2835–2846.
https://doi.org/10.4049/jimmunol.1701495
Published: 15 April 2018
View article titled, Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome
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Includes: Supplementary data
Journal Articles

Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity

Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, Siva Subramani, Durga Shiv Prasad, Preethi Karunanithi, Ratika Srivastava, Kamala Venkatesh, Sabariya Selvam, Prasad Krishnamurthy, T. Thanga Mariappan, Ajay Saxena, Li Fan, Dawn K. Stetsko, Deborah A. Holloway, Xin Li, Jun Zhu, Wen-Pin Yang, Stefan Ruepp, Satheesh Nair, Joseph Santella, John Duncia, John Hynes, Kim W. McIntyre, Julie A. Carman
Journal: The Journal of Immunology
J Immunol (2017) 198 (3): 1308–1319.
https://doi.org/10.4049/jimmunol.1600583
Published: 01 February 2017
View article titled, Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
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Includes: Supplementary data
Journal Articles

The MAP kinase, tumor progression locus 2 (Tpl2), activates the Akt/mTOR/S6 ribosomal protein pathway, inhibits Foxp3 expression and limits Treg immunosuppressive functions.

Xin Li, Nicole V Acuff, Angela Peeks, Rebecca Kirkland, Tamas Nagy, Wendy Tharpe Watford
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 133.9.
https://doi.org/10.4049/jimmunol.196.Supp.133.9
Published: 01 May 2016
View article titled, The MAP kinase, tumor progression locus 2 (Tpl2), activates the Akt/mTOR/S6 ribosomal protein pathway, inhibits Foxp3 expression and limits Treg immunosuppressive functions.
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Journal Articles

WX486, a novel inhibitor of BTK, demonstrated dose dependent inhibition of arthritis in mouse CIA and rat PG-PS models

Jian Lin, Chichung Chan, Chengde Wu, Chunli Shen, Shuhua Han, Xin Li, Tingting Guo, Shuhui Chen, Qiang Xiao, Lu Huang, Hailiang Chen, Ronghua Tu, Yong Xu, Xuehai Wang
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 210.15.
https://doi.org/10.4049/jimmunol.196.Supp.210.15
Published: 01 May 2016
View article titled, WX486, a novel inhibitor of BTK, demonstrated dose dependent inhibition of arthritis in mouse CIA and rat PG-PS models
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Journal Articles

Tumor progression locus 2 inhibits regulatory T cell development and immunosuppressive functions (LYM8P.640)

Xin Li, Nicole Acuff, Angela Peeks, Rebecca Kirkland, Kara Hardwick, Tamas Nagy, Wendy Watford
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 201.16.
https://doi.org/10.4049/jimmunol.194.Supp.201.16
Published: 01 May 2015
View article titled, Tumor progression locus 2 inhibits regulatory T cell development and immunosuppressive functions (LYM8P.640)
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Journal Articles

Tpl2 differentially regulates IFNγ and IL-17 production by CD4+ T cells in a T cell transfer model of colitis. (LYM8P.636)

Nicole Acuff, Xin Li, Rebecca Kirkland, Tamas Nagy, Wendy Watford
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 201.12.
https://doi.org/10.4049/jimmunol.194.Supp.201.12
Published: 01 May 2015
View article titled, Tpl2 differentially regulates IFNγ and IL-17 production by CD4<sup>+</sup> T cells in a T cell transfer model of colitis. (LYM8P.636)
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Journal Articles

TLR2 activation of TRIF controls both early inflammatory and late tolerance responses to Borrelia burgdorferi (180.11)

Tanja Petnicki-Ocwieja, Erin Chung, David Acosta, Laurie Ramos, Ok Shin, Sanjukta Ghosh, Lester Kobzik, Xin Li, Linden Hu
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 180.11.
https://doi.org/10.4049/jimmunol.188.Supp.180.11
Published: 01 May 2012
View article titled, TLR2 activation of TRIF controls both early inflammatory and late tolerance responses to Borrelia burgdorferi (180.11)
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Journal Articles

A cyclic AMP signal participates in T cell tissue retention by selectively blocking tissue egress. (173.21)

Jason Lees, Xin Li
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 173.21.
https://doi.org/10.4049/jimmunol.188.Supp.173.21
Published: 01 May 2012
View article titled, A cyclic AMP signal participates in T cell tissue retention by selectively blocking tissue egress. (173.21)
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Journal Articles

Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV+ Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation

Xin Li, Xinbing Han, Juliana Llano, Medhavi Bole, Xiuqin Zhou, Katharine Swan, Asha Anandaiah, Benjamin Nelson, Naimish R. Patel, Peter S. Reinach, Henry Koziel, Souvenir D. Tachado
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 6052–6058.
https://doi.org/10.4049/jimmunol.1101532
Published: 01 December 2011
View article titled, Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV<sup>+</sup> Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation
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