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Yang-Xin Fu
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Journal Articles

Zinc-c-di-AMP nanoparticles target and suppress tumors via endothelial STING activation and tumor associated macrophage reinvigoration

Kaiting Yang, Wenbo Han, Xiaomin Jiang, Andras Piffko, Jason Bugno, Chuanhui Han, Sirui Li, Hua Liang, Ziwan Xu, Wenxin Zheng, Liangliang Wang, Jiaai Wang, Xiaona Huang, Jenny P Ting, Yang-Xin Fu, Wenbin Lin, Ralph R. Weichselbaum
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 245.05.
https://doi.org/10.4049/jimmunol.210.Supp.245.05
Published: 01 May 2023
View article titled, Zinc-c-di-AMP nanoparticles target and suppress tumors via endothelial STING activation and tumor associated macrophage reinvigoration
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Journal Articles

Suppression of local IFN-I by commensal microbiota-derived butyrate impairs antitumor effects of ionizing radiation

Kaiting Yang, Yang-Xin Fu, Ralph R Weichselbaum
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 120.02.
https://doi.org/10.4049/jimmunol.208.Supp.120.02
Published: 01 May 2022
View article titled, Suppression of local IFN-I by commensal microbiota-derived butyrate impairs antitumor effects of ionizing radiation
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Journal Articles

CD160 serves as a negative regulator of NKT cells in acute hepatic injury

Kyung-Mi Lee, Gayoung Park, Tae-Jin Kim, Jeongmin Kim, Seon-Ah Lim, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 56.21.
https://doi.org/10.4049/jimmunol.202.Supp.56.21
Published: 01 May 2019
View article titled, CD160 serves as a negative regulator of NKT cells in acute hepatic injury
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Journal Articles

Sequential and liver-targeting activation of T cells overcomes PDL1-mediated viral persistence

Longchao Liu, Hua Peng, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 180.2.
https://doi.org/10.4049/jimmunol.200.Supp.180.2
Published: 01 May 2018
View article titled, Sequential and liver-targeting activation of T cells overcomes PDL1-mediated viral persistence
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Journal Articles

CTLA-4 limits anti-CD20-mediated tumor regression

Zhenhua Ren, Hua Peng, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 122.3.
https://doi.org/10.4049/jimmunol.200.Supp.122.3
Published: 01 May 2018
View article titled, CTLA-4 limits anti-CD20-mediated tumor regression
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Journal Articles

Targeting type I interferon tumor entry by anti-PD-L1 creates feedforward antitumor responses to overcome innate and adaptive resistance

Haidong Tang, Yong Liang, Jingya Guo, Xiangyan Qiu, Hua Peng, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 122.20.
https://doi.org/10.4049/jimmunol.200.Supp.122.20
Published: 01 May 2018
View article titled, Targeting type I interferon tumor entry by anti-PD-L1 creates feedforward antitumor responses to overcome innate and adaptive resistance
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Journal Articles

CD47-SIRPα axis restricts the therapeutic antitumor immunity through controlling tumor mitochondrial DNA-mediated innate sensing selectively in dendritic cells

Meng Xu, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 126.15.
https://doi.org/10.4049/jimmunol.198.Supp.126.15
Published: 01 May 2017
View article titled, CD47-SIRPα axis restricts the therapeutic antitumor immunity through controlling tumor mitochondrial DNA-mediated innate sensing selectively in dendritic cells
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Journal Articles

Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of Salmonella from the Gut Lumen and Generation of Anti-Salmonella Protective Immunity

Joanna A. Wroblewska, Yuan Zhang, Haidong Tang, Xiaohuan Guo, Cathryn Nagler, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2017) 198 (1): 55–60.
https://doi.org/10.4049/jimmunol.1600867
Published: 01 January 2017
View article titled, Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of <em>Salmonella</em> from the Gut Lumen and Generation of Anti-<em>Salmonella</em> Protective Immunity
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Includes: Supplementary data
Journal Articles

Differential role of ID2 in the group 3 innate lymphoid cells for the development of different gut associated lymphoid tissues.

Xiaohuan Guo, Wenyang Wang, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 52.8.
https://doi.org/10.4049/jimmunol.196.Supp.52.8
Published: 01 May 2016
View article titled, Differential role of ID2 in the group 3 innate lymphoid cells for the development of different gut associated lymphoid tissues.
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Journal Articles

Creating a T cell-inflamed tumor microenvironment overcomes resistance to checkpoint blockade

Haidong Tang, Yang Wang, Lukasz K Chlewicki, Yuan Zhang, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 74.2.
https://doi.org/10.4049/jimmunol.196.Supp.74.2
Published: 01 May 2016
View article titled, Creating a T cell-inflamed tumor microenvironment overcomes resistance to checkpoint blockade
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Journal Articles

Clearing Persistent Extracellular Antigen of Hepatitis B Virus: An Immunomodulatory Strategy To Reverse Tolerance for an Effective Therapeutic Vaccination

Danming Zhu, Longchao Liu, Dan Yang, Sherry Fu, Yingjie Bian, Zhichen Sun, Junming He, Lishan Su, Liguo Zhang, Hua Peng, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2016) 196 (7): 3079–3087.
https://doi.org/10.4049/jimmunol.1502061
Published: 01 April 2016
View article titled, Clearing Persistent Extracellular Antigen of Hepatitis B Virus: An Immunomodulatory Strategy To Reverse Tolerance for an Effective Therapeutic Vaccination
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Includes: Supplementary data
Journal Articles

Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity

Ifeoma Okwor, Guilian Xu, Haidong Tang, Yong Liang, Yang-Xin Fu, Jude E. Uzonna
Journal: The Journal of Immunology
J Immunol (2015) 195 (1): 194–202.
https://doi.org/10.4049/jimmunol.1401892
Published: 01 July 2015
View article titled, Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-<em>Leishmania</em> Immunity
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Journal Articles

Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype

Meng Xu, Mingyue Liu, Xuexiang Du, Sirui Li, Hang Li, Xiaozhu Li, Ying Li, Yang Wang, Zhihai Qin, Yang-Xin Fu, Shengdian Wang
Journal: The Journal of Immunology
J Immunol (2015) 194 (10): 4997–5006.
https://doi.org/10.4049/jimmunol.1402603
Published: 15 May 2015
View article titled, Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype
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Includes: Supplementary data
Journal Articles

Therapeutic Activity of High-Dose Intratumoral IFN-β Requires Direct Effect on the Tumor Vasculature

Robbert M. Spaapen, Michael Y. K. Leung, Mercedes B. Fuertes, Justin P. Kline, Long Zhang, Yan Zheng, Yang-Xin Fu, Xixi Luo, Kenneth S. Cohen, Thomas F. Gajewski
Journal: The Journal of Immunology
J Immunol (2014) 193 (8): 4254–4260.
https://doi.org/10.4049/jimmunol.1401109
Published: 15 October 2014
View article titled, Therapeutic Activity of High-Dose Intratumoral IFN-β Requires Direct Effect on the Tumor Vasculature
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Includes: Supplementary data
Journal Articles

Lymphotoxin-expressing marginal zone B cells support marginal zone integrity by maintaining the megakaryoblastic leukemia-1 expression (BA4P.221)

Hao Li, Hui-Chen Hsu, Qi Wu, PingAr Yang, Jun Li, Bao Luo, Yang-Xin Fu, Yong Zhou, John Mountz
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 46.12.
https://doi.org/10.4049/jimmunol.192.Supp.46.12
Published: 01 May 2014
View article titled, Lymphotoxin-expressing marginal zone B cells support marginal zone integrity by maintaining the megakaryoblastic leukemia-1 expression (BA4P.221)
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Journal Articles

Recruitment of adult thymic progenitors is regulated by lymphotoxin beta receptor (HEM4P.240)

Yaoyao Shi, Weiwei Wu, Yang-Xin Fu, Mingzhao Zhu
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 116.16.
https://doi.org/10.4049/jimmunol.192.Supp.116.16
Published: 01 May 2014
View article titled, Recruitment of adult thymic progenitors is regulated by lymphotoxin beta receptor (HEM4P.240)
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Journal Articles

Innate lymphoid cells protect host against intestinal pathogen through Id2 dependent IL-22 production and regulation of microbiota. (MUC4P.855)

Xiaohuan Guo, Barbara Kee, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 133.31.
https://doi.org/10.4049/jimmunol.192.Supp.133.31
Published: 01 May 2014
View article titled, Innate lymphoid cells protect host against intestinal pathogen through Id2 dependent IL-22 production and regulation of microbiota. (MUC4P.855)
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Journal Articles

Epithelial lymphotoxin beta receptor regulates embryonic medullary thymic epithelial cell development for central tolerance (BA14P.212)

Weiwei Wu, Yaoyao Shi, Yang-Xin Fu, Mingzhao Zhu
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 178.13.
https://doi.org/10.4049/jimmunol.192.Supp.178.13
Published: 01 May 2014
View article titled, Epithelial lymphotoxin beta receptor regulates embryonic medullary thymic epithelial cell development for central tolerance (BA14P.212)
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Journal Articles

Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell–Mediated Killing

Hua Liang, Liufu Deng, Steven Chmura, Byron Burnette, Nicole Liadis, Thomas Darga, Michael A. Beckett, Mark W. Lingen, MaryEllyn Witt, Ralph R. Weichselbaum, Yang-Xin Fu
Journal: The Journal of Immunology
J Immunol (2013) 190 (11): 5874–5881.
https://doi.org/10.4049/jimmunol.1202612
Published: 01 June 2013
View article titled, Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell–Mediated Killing
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Includes: Supplementary data
Journal Articles

Gut immunity and microbiome: from defense to metabolism (P3168)

Yang-Xin Fu, Vaibhav Upadhyay
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 61.9.
https://doi.org/10.4049/jimmunol.190.Supp.61.9
Published: 01 May 2013
View article titled, Gut immunity and microbiome: from defense to metabolism (P3168)
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