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Journal Articles

Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis

Chia-Ming Chang, Kuang-Hua Cheng, Tsai-Yin Wei, Meng-Ping Lu, Yi-Chen Chen, Yen-Ta Lu
Journal: The Journal of Immunology
J Immunol (2023) 210 (9): 1351–1362.
https://doi.org/10.4049/jimmunol.2200222
Published: 24 March 2023
View article titled, Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis
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Includes: Multimedia, Supplementary data
Journal Articles

Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells

Chan-Wang Jerry Lio, Heng-Yi Chen, Ana Almonte-Loya, Fang-Yun Lay, Eric Johnson, Edahi Gonzalez-Avalos, Jieyun Yin, Qin Ma, Daniel Wozniak, Fiona Harrison
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 168.09.
https://doi.org/10.4049/jimmunol.208.Supp.168.09
Published: 01 May 2022
View article titled, Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells
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Journal Articles

Vitamin C Potentiates Plasma Cell Differentiation via TET-mediated DNA Modifications at a Novel Prdm1 Distal Element

Heng-Yi Chen, Ana Alamonte-Loya, Fang-Yun Lay, Eric Johnson, Edahi Gonzalez-Avalos, Jieyun Yin, Daniel J. Wozniak, Hazem Ghoneim, Fiona Harrison, Chan-Wang Jerry Lio
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 98.20.
https://doi.org/10.4049/jimmunol.206.Supp.98.20
Published: 01 May 2021
View article titled, Vitamin C Potentiates Plasma Cell Differentiation via TET-mediated DNA Modifications at a Novel <em>Prdm1</em> Distal Element
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Journal Articles

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases

Heng-Yi Chen, Yen-Fei Wu, Feng-Cheng Chou, Yu-Hsuan Wu, Li-Tzu Yeh, Kuo-I Lin, Fu-Tong Liu, Huey-Kang Sytwu
Journal: The Journal of Immunology
J Immunol (2020) 204 (5): 1158–1172.
https://doi.org/10.4049/jimmunol.1901114
Published: 01 March 2020
View article titled, Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases
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Includes: Supplementary data
Journal Articles

Calnexin induces impairment of proliferation and effector function of CD4+ and CD8+ T cells and promotes tumor growth

Da Ma, Yi Chen Chen, Zhi Wang
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 196.6.
https://doi.org/10.4049/jimmunol.198.Supp.196.6
Published: 01 May 2017
View article titled, Calnexin induces impairment of proliferation and effector function of CD4+ and CD8+ T cells and promotes tumor growth
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Journal Articles

NLRP6 function in inflammatory monocytes reduces susceptibility to colitis in mice

Grace Yi Chen, Natasha Golovchenko, Bryan Schaf, Jiachen Chen, Kathryn Eaton, Sergey Seregin
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 126.14.
https://doi.org/10.4049/jimmunol.196.Supp.126.14
Published: 01 May 2016
View article titled, NLRP6 function in inflammatory monocytes reduces susceptibility to colitis in mice
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Journal Articles

Nlrp6 limits inflamation in mouse colon by regulating microbiota

Sergey S Seregin, Natasha Golovchenko, Bryan Schaf, Nicholas Pudlo, Jonathan Mitchell, Jiachen Chen, Patrick Schloss, Eric Martens, Kathryn Eaton, Grace Yi Chen
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 67.5.
https://doi.org/10.4049/jimmunol.196.Supp.67.5
Published: 01 May 2016
View article titled, Nlrp6 limits inflamation in mouse colon by regulating microbiota
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Journal Articles

Identification of Cell Surface Straight Chain Poly-N-Acetyl-Lactosamine Bearing Protein Ligands for VH4-34–Encoded Natural IgM Antibodies

Neelima M. Bhat, Christopher M. Adams, Yi Chen, Marcia M. Bieber, Nelson N. H. Teng
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5178–5188.
https://doi.org/10.4049/jimmunol.1501697
Published: 01 December 2015
View article titled, Identification of Cell Surface Straight Chain Poly-N-Acetyl-Lactosamine Bearing Protein Ligands for VH4-34–Encoded Natural IgM Antibodies
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Includes: Supplementary data
Journal Articles

A Subset of CD8αβ+ Invariant NKT Cells in a Humanized Mouse Model

Xiangshu Wen, Seil Kim, Ran Xiong, Michelle Li, Agnieszka Lawrenczyk, Xue Huang, Si-Yi Chen, Ping Rao, Gurdyal S. Besra, Paolo Dellabona, Giulia Casorati, Steven A. Porcelli, Omid Akbari, Mark A. Exley, Weiming Yuan
Journal: The Journal of Immunology
J Immunol (2015) 195 (4): 1459–1469.
https://doi.org/10.4049/jimmunol.1500574
Published: 15 August 2015
View article titled, A Subset of CD8αβ<sup>+</sup> Invariant NKT Cells in a Humanized Mouse Model
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Includes: Supplementary data
Journal Articles

Vibsanin B Preferentially Targets HSP90β, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis

Bai-Xin Ye, Xu Deng, Li-Dong Shao, Ying Lu, Run Xiao, Yi-Jie Liu, Yi Jin, Yin-Yin Xie, Yan Zhao, Liu-Fei Luo, Shun Ma, Ming Gao, Lian-Ru Zhang, Juan He, Wei-Na Zhang, Yi Chen, Cheng-Feng Xia, Min Deng, Ting-Xi Liu, Qin-Shi Zhao, Sai-Juan Chen, Zhu Chen
Journal: The Journal of Immunology
J Immunol (2015) 194 (9): 4489–4497.
https://doi.org/10.4049/jimmunol.1402798
Published: 01 May 2015
View article titled, Vibsanin B Preferentially Targets HSP90β, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis
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Includes: Supplementary data
Journal Articles

Developing an antibody targeting CεmX of mIgE for the treatment of IgE-mediated diseases (HYP4P.305)

Yueh-Hsuan Chan, Yu-Tzu Lee, Hung-Wen Chou, Pheidias Wu, Jiun-Bo Chen, Chau-Hong Li, Tien-Tien Cheng, Nien-Yi Chen, Tse-Wen Chang, Ko-Haung Lue
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 123.4.
https://doi.org/10.4049/jimmunol.194.Supp.123.4
Published: 01 May 2015
View article titled, Developing an antibody targeting CεmX of mIgE for the treatment of IgE-mediated diseases (HYP4P.305)
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Journal Articles

Estradiol Inhibits Th17 Cell Differentiation through Inhibition of RORγT Transcription by Recruiting the ERα/REA Complex to Estrogen Response Elements of the RORγT Promoter

Rong-Yi Chen, Yi-Ming Fan, Qiuyang Zhang, Sen Liu, Qingli Li, Guo-Lin Ke, Chen Li, Zongbing You
Journal: The Journal of Immunology
J Immunol (2015) 194 (8): 4019–4028.
https://doi.org/10.4049/jimmunol.1400806
Published: 15 April 2015
View article titled, Estradiol Inhibits Th17 Cell Differentiation through Inhibition of <em>RORγT</em> Transcription by Recruiting the ERα/REA Complex to Estrogen Response Elements of the <em>RORγT</em> Promoter
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Includes: Supplementary data
Journal Articles

Developing an antibody targeting CεmX of mIgE for the treatment of allergic and other IgE-mediated diseases (VAC6P.954)

Yueh-Hsuan Chan, Yu-Tzu Lee, Hung-Wen Chou, Pheidias C Wu, Jiun-Bo Chen, Chau-Hong Li, Tien-Tien Cheng, Nien-Yi Chen, Ko-Haung Lue, Tse-Wen Chang
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 140.15.
https://doi.org/10.4049/jimmunol.192.Supp.140.15
Published: 01 May 2014
View article titled, Developing an antibody targeting CεmX of mIgE for the treatment of allergic and other IgE-mediated diseases (VAC6P.954)
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Journal Articles

Histone H2A deubiquitinase MYSM1 is essential for dendritic cell development (P4488)

Haejung Won, Yuchia Chou, Tao Wang, Lindsey Jones, Xue Huang, Si-Yi Chen
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 52.61.
https://doi.org/10.4049/jimmunol.190.Supp.52.61
Published: 01 May 2013
View article titled, Histone H2A deubiquitinase MYSM1 is essential for dendritic cell development (P4488)
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Journal Articles

CD8 T Cell-Initiated Blood–Brain Barrier Disruption Is Independent of Neutrophil Support

Holly L. Johnson, Yi Chen, Fang Jin, Lisa M. Hanson, Jeffrey D. Gamez, Istvan Pirko, Aaron J. Johnson
Journal: The Journal of Immunology
J Immunol (2012) 189 (4): 1937–1945.
https://doi.org/10.4049/jimmunol.1200658
Published: 15 August 2012
View article titled, CD8 T Cell-Initiated Blood–Brain Barrier Disruption Is Independent of Neutrophil Support
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Journal Articles

CϵmX peptide-carrying HBcAg virus-like particles induced antibodies that down-regulate mIgE-B cells (53.7)

Chien-Jen Lin, Nien-Yi Nien-Yi Chen, Jiun-Bo Chen, Chien-Sheng Lu, Alfur Fu-Hsin Hung, Yu-Yu Shiung, Pheidias C. Wu, Rong-Long Pan, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 53.7.
https://doi.org/10.4049/jimmunol.188.Supp.53.7
Published: 01 May 2012
View article titled, CϵmX peptide-carrying HBcAg virus-like particles induced antibodies that down-regulate mIgE-B cells (53.7)
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Journal Articles

IL-23 promotes autoimmune Th17 memory formation and function (59.6)

Mandy McGeachy, Christopher Haines, Yi Chen, Wendy Blumenschein, Terri McClanahan, Daniel Cua
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 59.6.
https://doi.org/10.4049/jimmunol.188.Supp.59.6
Published: 01 May 2012
View article titled, IL-23 promotes autoimmune Th17 memory formation and function (59.6)
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Journal Articles

Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion

Seth B. Coffelt, Yung-Yi Chen, Munitta Muthana, Abigail F. Welford, Andrea O. Tal, Alexander Scholz, Karl H. Plate, Yvonne Reiss, Craig Murdoch, Michele De Palma, Claire E. Lewis
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 4183–4190.
https://doi.org/10.4049/jimmunol.1002802
Published: 01 April 2011
View article titled, Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion
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Includes: Supplementary data
Journal Articles

The lipid raft hinders antibodies from binding to the external segment of the membrane-anchor peptide of mIgA (52.19)

Alfur Hung, Jiun-Bo Chen, Chien-Sheng Lu, Nien-Yi Chen, Hui-Ming Yu, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 52.19.
https://doi.org/10.4049/jimmunol.186.Supp.52.19
Published: 01 April 2011
View article titled, The lipid raft hinders antibodies from binding to the external segment of the membrane-anchor peptide of mIgA (52.19)
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Targeting and manipulating mIgD-expressing B cells by anti-migis-δ monoclonal antibodies (52.18)

Nien-Yi Chen, Alfur Hung, Hui-Ming Yu, Hwan-You Chang, Tse-Wen Chang
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 52.18.
https://doi.org/10.4049/jimmunol.186.Supp.52.18
Published: 01 April 2011
View article titled, Targeting and manipulating mIgD-expressing B cells by anti-migis-δ monoclonal antibodies (52.18)
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