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Yvonne M. Mueller
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Journal Articles

TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model

Melisa D. Castro Eiro, Kou Hioki, Ling Li, Merel E. P. Wilmsen, Caoimhe H. Kiernan, Inge Brouwers-Haspels, Marjan van Meurs, Manzhi Zhao, Harm de Wit, Dwin G. B. Grashof, Harmen J. G. van de Werken, Yvonne M. Mueller, Christopher Schliehe, Burcu Temizoz, Kouji Kobiyama, Ken J. Ishii, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2024) 212 (3): 455–465.
https://doi.org/10.4049/jimmunol.2300038
Published: 08 December 2023
View article titled, TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model
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Includes: Supplementary data
Journal Articles

ITK inhibition improves the response to immune checkpoint blockade in solid tumors

Ling Li, Manzhi Zhao, Caoimhe H Kiernan, Melisa D Castro Eiro, Floris Dammeijer, Marjan van Meurs, Inge Brouwers-Haspels, Merel Wilmsen, Dwin G.B Grashof, Harmen J.G van de Werken, Rudi W Hendriks, Joachim G Aerts, Yvonne M Mueller, Peter D Katsikis
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 230.02.
https://doi.org/10.4049/jimmunol.210.Supp.230.02
Published: 01 May 2023
View article titled, ITK inhibition improves the response to immune checkpoint blockade in solid tumors
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Journal Articles

A combination of TLR9 and STING agonists induces potent neopeptide-specific T cell immunity and improves ICB efficacy in tumor models

Kou Hioki, Melisa D. Castro Eiro, Ling Li, Merel E.P. Wilmsen, Caoimhe H. Kiernan, Inge Brouwers-Haspels, Marjan van Meurs, Kevin de Vos, Marlous Wildemans, Manzhi Zhao, Harm de Wit, Dwin G.B. Grashof, Harmen J.G. van de Werken, Yvonne M. Mueller, Christopher Schliehe, Ken J. Ishii, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 145.05.
https://doi.org/10.4049/jimmunol.210.Supp.145.05
Published: 01 May 2023
View article titled, A combination of TLR9 and STING agonists induces potent neopeptide-specific T cell immunity and improves ICB efficacy in tumor models
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Journal Articles

MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses

Jennifer L. Hope, Manzhi Zhao, Christopher J. Stairiker, Caoimhe H. Kiernan, Alison J. Carey, Yvonne M. Mueller, Marjan van Meurs, Inge Brouwers-Haspels, Dennis C. Otero, Eun-Ah Bae, Hannah A. Faso, Alex Maas, Hans de Looper, Paolo M. Fortina, Isidore Rigoutsos, Linda M. Bradley, Stefan J. Erkeland, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 603–617.
https://doi.org/10.4049/jimmunol.2000621
Published: 01 February 2022
View article titled, MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8<sup>+</sup> T Cell Responses
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Includes: Supplementary data
Journal Articles

Establishment And Application of An in Vitro Cd8+ T Cell Exhaustion System

Manzhi Zhao, Caoimhe H. Kiernan, Leticia G. Leon, Marjan van Meurs, Inge Brouwers-Haspels, Yvonne M Mueller, Peter D Katsikis
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 77.11.
https://doi.org/10.4049/jimmunol.204.Supp.77.11
Published: 01 May 2020
View article titled, Establishment And Application of An in Vitro Cd8+ T Cell Exhaustion System
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Journal Articles

Identification of a core miRNA signature unique to exhausted cytotoxic CD8+ T cells

Caoimhe H. Kiernan, Jennifer L Hope, Leticia G. Leon, Manzhi Zhao, Marjan van Meurs, Inge Brouwers-Haspels, Paulette van Strien, Erik Bindels, Remco M. Hoogenboezem, Yunlei Li, Andrew P. Stubbs, Dietmar Zehn, Yvonne M Mueller, Stefan J. Erkeland, Peter D Katsikis
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 165.9.
https://doi.org/10.4049/jimmunol.204.Supp.165.9
Published: 01 May 2020
View article titled, Identification of a core miRNA signature unique to exhausted cytotoxic CD8+ T cells
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Journal Articles

The CD8+ T-cell receptor (TCR) repertoire in extremely preterm neonates is highly shared and convergent

Alison J Carey, Jennifer L Hope, Adam J Fike, Yvonne M Mueller, Linda T Nguyen, Ogan K Kumova, David BH Van Zessen, Mirjam van der Burg, Peter D Katsikis
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 202.10.
https://doi.org/10.4049/jimmunol.198.Supp.202.10
Published: 01 May 2017
View article titled, The CD8<sup>+</sup> T-cell receptor (TCR) repertoire in extremely preterm neonates is highly shared and convergent
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Journal Articles

MicroRNA-155 regulates T-bet expression in anti-viral CD8+ T cells

Jennifer L Hope, Christopher Stairiker, Panagiota Spantidea, Donald Tom Gracias, Alison J Carey, Marjan van Meurs, Inge Brouwers-Haspels, Adam J Fike, Laurine Rijsbergen, Yvonne M Mueller, Joseph A Fraietta, Roos Klop, Stefan Erkeland, Peter D Katsikis
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 121.5.
https://doi.org/10.4049/jimmunol.198.Supp.121.5
Published: 01 May 2017
View article titled, MicroRNA-155 regulates T-bet expression in anti-viral CD8+ T cells
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Journal Articles

Rapid Evolution of the CD8+ TCR Repertoire in Neonatal Mice

Alison J. Carey, Donald T. Gracias, Jillian L. Thayer, Alina C. Boesteanu, Ogan K. Kumova, Yvonne M. Mueller, Jennifer L. Hope, Joseph A. Fraietta, David B. H. van Zessen, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2016) 196 (6): 2602–2613.
https://doi.org/10.4049/jimmunol.1502126
Published: 15 March 2016
View article titled, Rapid Evolution of the CD8<sup>+</sup> TCR Repertoire in Neonatal Mice
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Includes: Supplementary data
Journal Articles

Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8+ T Cell Responses during Acute Viral and Intracellular Bacterial Infections

Donald T. Gracias, Alina C. Boesteanu, Joseph A. Fraietta, Jennifer L. Hope, Alison J. Carey, Yvonne M. Mueller, Omkar U. Kawalekar, Adam J. Fike, Carl H. June, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2016) 196 (3): 1186–1198.
https://doi.org/10.4049/jimmunol.1501890
Published: 01 February 2016
View article titled, Phosphatidylinositol 3-Kinase p110δ Isoform Regulates CD8<sup>+</sup> T Cell Responses during Acute Viral and Intracellular Bacterial Infections
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Includes: Supplementary data
Journal Articles

Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8+ T Cell Responses during the Effector Phase In Vivo

Douglas V. Dolfi, Priyanka A. Duttagupta, Alina C. Boesteanu, Yvonne M. Mueller, Caspian H. Oliai, Annie B. Borowski, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2011) 186 (8): 4599–4608.
https://doi.org/10.4049/jimmunol.1001972
Published: 15 April 2011
View article titled, Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8<sup>+</sup> T Cell Responses during the Effector Phase In Vivo
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Includes: Supplementary data
Journal Articles

CD8+ Cell Depletion of SHIV89.6P-Infected Macaques Induces CD4+ T Cell Proliferation that Contributes to Increased Viral Loads

Yvonne M. Mueller, Duc H. Do, Jean D. Boyer, Muhamuda Kader, Joseph J. Mattapallil, Mark G. Lewis, David B. Weiner, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2009) 183 (8): 5006–5012.
https://doi.org/10.4049/jimmunol.0900141
Published: 15 October 2009
View article titled, CD8<sup>+</sup> Cell Depletion of SHIV89.6P-Infected Macaques Induces CD4<sup>+</sup> T Cell Proliferation that Contributes to Increased Viral Loads
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Journal Articles

Differential Association of Programmed Death-1 and CD57 with Ex Vivo Survival of CD8+ T Cells in HIV Infection

Constantinos Petrovas, Benjamin Chaon, David R. Ambrozak, David A. Price, J. Joseph Melenhorst, Brenna J. Hill, Christof Geldmacher, Joseph P. Casazza, Pratip K. Chattopadhyay, Mario Roederer, Daniel C. Douek, Yvonne M. Mueller, Jeffrey M. Jacobson, Viraj Kulkarni, Barbara K. Felber, George N. Pavlakis, Peter D. Katsikis, Richard A. Koup
Journal: The Journal of Immunology
J Immunol (2009) 183 (2): 1120–1132.
https://doi.org/10.4049/jimmunol.0900182
Published: 15 July 2009
View article titled, Differential Association of Programmed Death-1 and CD57 with Ex Vivo Survival of CD8<sup>+</sup> T Cells in HIV Infection
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Includes: Supplementary data
Journal Articles

Chronic Antigen Stimulation Alone Is Sufficient to Drive CD8+ T Cell Exhaustion

Christine M. Bucks, Jillian A. Norton, Alina C. Boesteanu, Yvonne M. Mueller, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2009) 182 (11): 6697–6708.
https://doi.org/10.4049/jimmunol.0800997
Published: 01 June 2009
View article titled, Chronic Antigen Stimulation Alone Is Sufficient to Drive CD8<sup>+</sup> T Cell Exhaustion
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Journal Articles

A critical role for microRNA miR-155 in CD8+ T cell responses (90.23)

ERIETTA STELEKATI, ALINA C. BOESTEANU, DONALD T. GRACIAS, YVONNE M. MUELLER, ELENA VIGORITO, JILLIAN A. NORTON, MARTIN TURNER, PETER D. KATSIKIS
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 90.23.
https://doi.org/10.4049/jimmunol.182.Supp.90.23
Published: 01 April 2009
View article titled, A critical role for microRNA miR-155 in CD8+ T cell responses (90.23)
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Increased IL-15 Production Is Associated with Higher Susceptibility of Memory CD4 T Cells to Simian Immunodeficiency Virus during Acute Infection

Matthew D. Eberly, Muhamuda Kader, Wail Hassan, Kenneth A. Rogers, Jianzhong Zhou, Yvonne M. Mueller, Mary J. Mattapallil, Michael Piatak, Jr., Jeffrey D. Lifson, Peter D. Katsikis, Mario Roederer, Francois Villinger, Joseph J. Mattapallil
Journal: The Journal of Immunology
J Immunol (2009) 182 (3): 1439–1448.
https://doi.org/10.4049/jimmunol.182.3.1439
Published: 01 February 2009
View article titled, Increased IL-15 Production Is Associated with Higher Susceptibility of Memory CD4 T Cells to Simian Immunodeficiency Virus during Acute Infection
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Includes: Supplementary data
Journal Articles

Early Divergence in Neutrophil Apoptosis between Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infections of Nonhuman Primates

Carole Elbim, Valerie Monceaux, Yvonne M. Mueller, Mark G. Lewis, Stephanie François, Ousmane Diop, Khadija Akarid, Bruno Hurtrel, Marie-Anne Gougerot-Pocidalo, Yves Lévy, Peter D. Katsikis, Jerome Estaquier
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8613–8623.
https://doi.org/10.4049/jimmunol.181.12.8613
Published: 15 December 2008
View article titled, Early Divergence in Neutrophil Apoptosis between Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infections of Nonhuman Primates
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Journal Articles

IL-15 Treatment during Acute Simian Immunodeficiency Virus (SIV) Infection Increases Viral Set Point and Accelerates Disease Progression despite the Induction of Stronger SIV-Specific CD8+ T Cell Responses

Yvonne M. Mueller, Duc H. Do, Susan R. Altork, Carol M. Artlett, Edward J. Gracely, Christos D. Katsetos, Agustin Legido, Francois Villinger, John D. Altman, Charles R. Brown, Mark G. Lewis, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2008) 180 (1): 350–360.
https://doi.org/10.4049/jimmunol.180.1.350
Published: 01 January 2008
View article titled, IL-15 Treatment during Acute Simian Immunodeficiency Virus (SIV) Infection Increases Viral Set Point and Accelerates Disease Progression despite the Induction of Stronger SIV-Specific CD8<sup>+</sup> T Cell Responses
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Journal Articles

Memory CD8+ T Cells Require CD28 Costimulation

Annie B. Borowski, Alina C. Boesteanu, Yvonne M. Mueller, Caterina Carafides, David J. Topham, John D. Altman, Stephen R. Jennings, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 6494–6503.
https://doi.org/10.4049/jimmunol.179.10.6494
Published: 15 November 2007
View article titled, Memory CD8<sup>+</sup> T Cells Require CD28 Costimulation
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Complement C5a Receptor Is Essential for the Optimal Generation of Antiviral CD8+ T Cell Responses

Alfred H. J. Kim, Ioannis D. Dimitriou, M. Claire H. Holland, Dimitrios Mastellos, Yvonne M. Mueller, John D. Altman, John D. Lambris, Peter D. Katsikis
Journal: The Journal of Immunology
J Immunol (2004) 173 (4): 2524–2529.
https://doi.org/10.4049/jimmunol.173.4.2524
Published: 15 August 2004
View article titled, Complement C5a Receptor Is Essential for the Optimal Generation of Antiviral CD8<sup>+</sup> T Cell Responses
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