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Zhichao Fan
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Journal Articles

Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis

Sophia P. M. Sok, Kaitlyn Pipkin, Narcis I. Popescu, Megan Reidy, Bin Li, Holly Van Remmen, Mike Kinter, Xiao-Hong Sun, Zhichao Fan, Meng Zhao
Journal: The Journal of Immunology
J Immunol (2024) 213 (7): 941–951.
https://doi.org/10.4049/jimmunol.2400246
Published: 19 August 2024
View article titled, Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis
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Includes: Supplementary data
Journal Articles

Distinct roles of kindlin-3 and talin-1 in neutrophil beta2 integrin clustering

Yuanyuan Wu, Lai Wen, Klaus Ley, Zhichao Fan
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 79.01.
https://doi.org/10.4049/jimmunol.210.Supp.79.01
Published: 01 May 2023
View article titled, Distinct roles of kindlin-3 and talin-1 in neutrophil beta2 integrin clustering
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Journal Articles

Sex-specific and immune-cell-specific contributions of CD18 in myocardial ischemia-reperfusion injury

Zhichao Fan, Wei Liu, Chunxia G Cronin, Lai Wen, Klaus Ley, Bruce T Liang
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 70.07.
https://doi.org/10.4049/jimmunol.210.Supp.70.07
Published: 01 May 2023
View article titled, Sex-specific and immune-cell-specific contributions of CD18 in myocardial ischemia-reperfusion injury
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Journal Articles

Nexinhib20 Inhibits Neutrophil Adhesion and β2 Integrin Activation by Antagonizing Rac-1–Guanosine 5′-Triphosphate Interaction

Wei Liu, Chunxia G. Cronin, Ziming Cao, Chengliang Wang, Jianbin Ruan, Sunitha Pulikkot, Alexxus Hall, Hao Sun, Alex Groisman, Yunfeng Chen, Anthony T. Vella, Liang Hu, Bruce T. Liang, Zhichao Fan
Journal: The Journal of Immunology
J Immunol (2022) 209 (8): 1574–1585.
https://doi.org/10.4049/jimmunol.2101112
Published: 15 October 2022
View article titled, Nexinhib20 Inhibits Neutrophil Adhesion and β<sub>2</sub> Integrin Activation by Antagonizing Rac-1–Guanosine 5′-Triphosphate Interaction
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Includes: Supplementary data
Journal Articles

Nexinhib20 inhibits neutrophil adhesion and β2 integrin activation to prevent myocardial ischemia-reperfusion injury

Zhichao Fan, Wei Liu, Chunxia G Cronin, Chengliang Wang, Jianbin Ruan, Jennifer L Johnson, Sergio Catz, Hao Sun, Alex Groisman, Yunfeng Chen, Liang Hu, Anthony T Vella, Bruce Liang
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 105.01.
https://doi.org/10.4049/jimmunol.208.Supp.105.01
Published: 01 May 2022
View article titled, Nexinhib20 inhibits neutrophil adhesion and β2 integrin activation to prevent myocardial ischemia-reperfusion injury
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Journal Articles

Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells

Frederic Lagarrigue, Boyang Tan, Qinyi Du, Zhichao Fan, Miguel A. Lopez-Ramirez, Alexandre R. Gingras, Hsin Wang, Weiwei Qi, Hao Sun
Journal: The Journal of Immunology
J Immunol (2022) 208 (6): 1378–1388.
https://doi.org/10.4049/jimmunol.2100843
Published: 15 March 2022
View article titled, Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice

Zhichao Fan, Elise Pitmon, Lai Wen, Jacqueline Miller, Erik Ehinger, Rana Herro, Wei Liu, Ju Chen, Zbigniew Mikulski, Douglas J. Conrad, Alex Marki, Marco Orecchioni, Puja Kumari, Yanfang Peipei Zhu, Paola M. Marcovecchio, Catherine C. Hedrick, Craig A. Hodges, Vijay A. Rathinam, Kepeng Wang, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 745–752.
https://doi.org/10.4049/jimmunol.1901171
Published: 01 February 2022
View article titled, Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice
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Includes: Multimedia, Supplementary data
Journal Articles

Mitofusin-2 regulates leukocyte adhesion through the maturation of beta2 integrin activation in differentiation

Zhichao Fan, Wei Liu, Yueyang Wang, Alan Y Hsu, Tao Lin, Hao Sun, Joel S Pachter, Alex Groisman, Matthew Imperioli, Fernanda Wajnsztajn Yungher, Liang Hu, Penghua Wang, Qing Deng
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 11.01.
https://doi.org/10.4049/jimmunol.206.Supp.11.01
Published: 01 May 2021
View article titled, Mitofusin-2 regulates leukocyte adhesion through the maturation of beta2 integrin activation in differentiation
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Journal Articles

Recruitment of kindlin-3 to plasma membrane through its PH domain precedes high affinity β2 integrin activation and neutrophil arrest

Lai Wen, Alex Marki, Payel Roy, Sara McArdle, Hao Sun, Zhichao Fan, Alexandre R. Gingras, Mark H Ginsberg, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 220.7.
https://doi.org/10.4049/jimmunol.204.Supp.220.7
Published: 01 May 2020
View article titled, Recruitment of kindlin-3 to plasma membrane through its PH domain precedes high affinity β<sub>2</sub> integrin activation and neutrophil arrest
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Journal Articles

Kindlin-3 organizes a ring of clustered high affinity β2 integrins during human neutrophil spreading under flow

Zhichao Fan, Lai Wen, Yi-Ting Yeh, William B Kiosses, Edgar Gutierrez, Alex Groisman, Joshua Francois, Juan C Lasheras, Juan C del Alamo, Shu Chien, Mark H Ginsberg, Brian G Petrich, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 220.1.
https://doi.org/10.4049/jimmunol.204.Supp.220.1
Published: 01 May 2020
View article titled, Kindlin-3 organizes a ring of clustered high affinity β<sub>2</sub> integrins during human neutrophil spreading under flow
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Journal Articles

Olfactory receptor 2 (Olfr2) and its human ortholog OR6A2 expressed in macrophages drive NLRP3 inflammasome activation and exacerbate atherosclerosis in mice

Marco Orecchioni, Kouji Kobiyama, Holger Winkels, Yanal Ghosheh, Sara McArdle, Zbigniew Mikulski, Zhichao Fan, Lai Wen, Yunmin Jung, Payel Roy, Yukiko Myamoto, Hiroaki Matsunami, Lars Eckmann, Eicke Latz, Zeneng Wang, Stanley L Hazen, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 68.22.
https://doi.org/10.4049/jimmunol.204.Supp.68.22
Published: 01 May 2020
View article titled, Olfactory receptor 2 (Olfr2) and its human ortholog OR6A2 expressed in macrophages drive NLRP3 inflammasome activation and exacerbate atherosclerosis in mice
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Journal Articles

Bone marrow transplantation rescues monocyte recruitment defect and improves cystic fibrosis in mice

Zhichao Fan, Jacqueline Miller, Rana Herro, Erik Ehinger, Douglas J. Conrad, Zbigniew Mikulski, Yanfang Peipei Zhu, Paola M. Marcovecchio, Catherine C. Hedrick, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 182.1.
https://doi.org/10.4049/jimmunol.202.Supp.182.1
Published: 01 May 2019
View article titled, Bone marrow transplantation rescues monocyte recruitment defect and improves cystic fibrosis in mice
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Journal Articles

CD11bhigh CD11clow Ialow DCs regulate T-cells activation in the experimental autoimmune uveitis

Wei Lin, Xin Wang, Zhichao Fan
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 47.23.
https://doi.org/10.4049/jimmunol.200.Supp.47.23
Published: 01 May 2018
View article titled, CD11b<sup>high</sup> CD11c<sup>low</sup> Ia<sup>low</sup> DCs regulate T-cells activation in the experimental autoimmune uveitis
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Journal Articles

Neutrophil recruitment limited by high affinity bent β2 integrin binding ligand in cis

Zhichao Fan, Sara McArdle, Zbigniew Mikulski, Edgar Gutierrez, Mark Ginsberg, Alex Groisman, Klaus Ley
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 119.5.
https://doi.org/10.4049/jimmunol.196.Supp.119.5
Published: 01 May 2016
View article titled, Neutrophil recruitment limited by high affinity bent β<sub>2</sub> integrin binding ligand in cis
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