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Cutting Edge: Influenza-Induced CD11a^lo Airway CD103⁺ Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation

Stephanie van de Wall, Sequoia Crooks, Steven M. Varga, Vladimir P. Badovinac, John T. Harty

J Immunol ji2200931.

DOI: https://doi.org/10.4049/jimmunol.2200931

Published: 13 March 2023

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Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice

Arun Cumpelik, Evan Cody, Samuel Mon-Wei Yu, Emilie K. Grasset, David Dominguez-Sola, Andrea Cerutti, Peter S. Heeger

J Immunol (2023) 210 (1): 19–23.

DOI: https://doi.org/10.4049/jimmunol.2200410

Published: 01 January 2023

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Cutting Edge: CCR9 Promotes CD8⁺ T Cell Recruitment to the Brain during Congenital Cytomegalovirus Infection

Zachary T. Hilt, Wisler Charles, Katarina E. Cheng, Cybelle Tabilas, Megan Steinhilber, Samantha P. Wesnak, Norah L. Smith, Chris B. Schaffer, Brian D. Rudd

J Immunol (2022) 209 (12): 2281–2286.

DOI: https://doi.org/10.4049/jimmunol.2200578

Published: 15 December 2022

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Cutting Edge: mTORC2 Regulates CD8⁺ Effector and Memory T Cell Differentiation through Serum and Glucocorticoid Kinase 1

Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell

J Immunol (2022) 209 (12): 2287–2291.

DOI: https://doi.org/10.4049/jimmunol.2100669

Published: 15 December 2022

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Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8⁺ T Cells in the Face of Pre-Existing Humoral Immunity

Ming Z. M. Zheng, Svenja Fritzlar, Zhongfang Wang, Tiong Kit Tan, Katherine Kedzierska, Alain Townsend, Patrick C. Reading, Linda M. Wakim

J Immunol (2022) 209 (10): 1832–1836.

DOI: https://doi.org/10.4049/jimmunol.2200577

Published: 15 November 2022

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Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors

Vanessa Espinosa, Orchi Dutta, Lena J. Heung, Keyi Wang, Yun-Juan Chang, Patricia Soteropoulos, Tobias M. Hohl, Mark C. Siracusa, Amariliz Rivera

J Immunol (2022) 209 (10): 1827–1831.

DOI: https://doi.org/10.4049/jimmunol.2200430

Published: 15 November 2022

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Cutting Edge: Bispecific γδ T Cell Engager Containing Heterodimeric BTN2A1 and BTN3A1 Promotes Targeted Activation of Vγ9Vδ2⁺ T Cells in the Presence of Costimulation by CD28 or NKG2D

Anne Y. Lai, Arpita Patel, Faraha Brewer, Kinsley Evans, Kellsey Johannes, Louis E. González, Kyung Jin Yoo, George Fromm, Keith Wilson, Taylor H. Schreiber, Suresh de Silva

J Immunol (2022) 209 (8): 1475–1480.

DOI: https://doi.org/10.4049/jimmunol.2200185

Published: 15 October 2022

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Cutting Edge: The Expression of Transcription Inhibitor GFI1 Is Induced by Retinoic Acid to Rein in Th9 Polarization

Leon Friesen, Raymond Kostlan, Qingyang Liu, Hao Yu, Jinfang Zhu, Nicholas Lukacs, Chang H. Kim

J Immunol (2022) 209 (7): 1237–1242.

DOI: https://doi.org/10.4049/jimmunol.2200328

Published: 01 October 2022

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Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction

Jonathan Woods, Sarah E. Pemberton, Andrea D. Largent, Kristy Chiang, Denny Liggitt, Mohamed Oukka, David J. Rawlings, Shaun W. Jackson

J Immunol (2022) 209 (6): 1033–1038.

DOI: https://doi.org/10.4049/jimmunol.2100920

Published: 15 September 2022

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Cutting Edge: Hyperinflammatory Monocytes Expressing CD56 Abound in Severe COVID-19 Patients

In Special Collection:

COVID-19, SARS, and MERS Articles

Stefania Campana, Claudia De Pasquale, Giacomo Sidoti Migliore, Gaetana Pezzino, Riccardo Cavaliere, Emmanuele Venanzi Rullo, Giuseppe Nunnari, Gaetano Caramori, Antonio David, Irene Bonaccorsi, Teresa Pollicino, Paolo Carrega, Guido Ferlazzo

J Immunol (2022) 209 (4): 655–659.

DOI: https://doi.org/10.4049/jimmunol.2200021

Published: 15 August 2022

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Cutting Edge: Promoting T Cell Factor 1⁺ T Cell Self-Renewal to Improve Programmed Cell Death Protein 1 Blockade

Peter H. Wang, Robert Washburn, Rohan Maniar, Michael Mu, Olivia Ringham, Radomir Kratchmarov, Brian S. Henick, Steven L. Reiner

J Immunol (2022) 209 (4): 660–664.

DOI: https://doi.org/10.4049/jimmunol.2200317

Published: 15 August 2022

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Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved

In Special Collection:

COVID-19, SARS, and MERS Articles

Mladen Jergović, Christopher P. Coplen, Jennifer L. Uhrlaub, Shawn C. Beitel, Jefferey L. Burgess, Karen Lutrick, Katherine D. Ellingson, Makiko Watanabe, Janko Nikolich-Žugich

J Immunol (2022) 208 (11): 2461–2465.

DOI: https://doi.org/10.4049/jimmunol.2200175

Published: 01 June 2022

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Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil

In Special Collection:

COVID-19, SARS, and MERS Articles

Hyon-Xhi Tan, Kathleen M. Wragg, Hannah G. Kelly, Robyn Esterbauer, Benjamin J. Dixon, Jillian S. Y. Lau, Katie L. Flanagan, Carolien E. van de Sandt, Katherine Kedzierska, James H. McMahon, Adam K. Wheatley, Jennifer A. Juno, Stephen J. Kent

J Immunol (2022) 208 (10): 2267–2271.

DOI: https://doi.org/10.4049/jimmunol.2101199

Published: 15 May 2022

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Cutting Edge: Unconventional CD8⁺ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope

Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud de Ru, Peter A. van Veelen, Jamie Rossjohn, Stephanie Gras, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk

J Immunol (2022) 208 (8): 1851–1856.

DOI: https://doi.org/10.4049/jimmunol.2101208

Published: 15 April 2022

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Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice

David J. Friedman, Monika Kizerwetter, Paul Belmonte, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Michael J. Shapiro, Haidong Dong, Virginia Smith Shapiro

J Immunol (2022) 208 (8): 1845–1850.

DOI: https://doi.org/10.4049/jimmunol.2101165

Published: 15 April 2022

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Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine–Induced Immune Responses in Multiple Sclerosis Patients

In Special Collection:

COVID-19, SARS, and MERS Articles

Yevgeniy Yuzefpolskiy, Peter Morawski, Mitch Fahning, Cate Speake, Sandra Lord, Anu Chaudhary, Chihiro Morishima, Mark H. Wener, Mariko Kita, Lucas McCarthy, Jane H. Buckner, Daniel J. Campbell, Estelle Bettelli

J Immunol (2022) 208 (7): 1519–1524.

DOI: https://doi.org/10.4049/jimmunol.2101142

Published: 01 April 2022

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Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4⁺ T Cells following BNT162b2 Vaccination in the Elderly

In Special Collection:

COVID-19, SARS, and MERS Articles

Lil Meyer-Arndt, Tatjana Schwarz, Lucie Loyal, Larissa Henze, Beate Kruse, Manuela Dingeldey, Kübrah Gürcan, Zehra Uyar-Aydin, Marcel A. Müller, Christian Drosten, Friedemann Paul, Leif E. Sander, Ilja Demuth, Roland Lauster, Claudia Giesecke-Thiel, Julian Braun, Victor M. Corman, Andreas Thiel

J Immunol (2022) 208 (5): 1001–1005.

DOI: https://doi.org/10.4049/jimmunol.2100990

Published: 01 March 2022

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Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4⁺ T Cell Viability and Proliferation

Rebecca R. Crowther, Stephanie M. Schmidt, Shannon M. Lange, Melanie C. McKell, Michelle C. Robillard, Junfang Zhao, Wendy D. Haffey, Michael A. Wyder, Kenneth D. Greis, Kenneth D. R. Setchell, Joseph E. Qualls

J Immunol (2022) 208 (4): 793–798.

DOI: https://doi.org/10.4049/jimmunol.2100652

Published: 15 February 2022

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Cutting Edge: Subunit Booster Vaccination Confers Sterilizing Immunity against Liver-Stage Malaria in Mice Initially Primed with a Weight-Normalized Dose of Radiation-Attenuated Sporozoites

Mitchell N. Lefebvre, Lisa L. Drewry, Lecia L. Pewe, Lisa S. Hancox, Arturo Reyes-Sandoval, John T. Harty

J Immunol (2021) 207 (11): 2631–2635.

DOI: https://doi.org/10.4049/jimmunol.2100818

Published: 01 December 2021

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Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis

Asanga Weliwitigoda, Pushpalatha Palle, Melissa Gessner, Nicholas W. Hubbard, Mohamed Oukka, Estelle Bettelli

J Immunol (2021) 207 (10): 2417–2422.

DOI: https://doi.org/10.4049/jimmunol.2001294

Published: 15 November 2021

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2 3 4 5

NARROW

Cutting Edge: Influenza-Induced CD11a^lo Airway CD103⁺ Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation

Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice

Cutting Edge: CCR9 Promotes CD8⁺ T Cell Recruitment to the Brain during Congenital Cytomegalovirus Infection

Cutting Edge: mTORC2 Regulates CD8⁺ Effector and Memory T Cell Differentiation through Serum and Glucocorticoid Kinase 1

Cutting Edge: High-Dose Live Attenuated Influenza Vaccines Elicit Pulmonary Tissue-Resident Memory CD8⁺ T Cells in the Face of Pre-Existing Humoral Immunity

Cutting Edge: Neutrophils License the Maturation of Monocytes into Effective Antifungal Effectors

Cutting Edge: Bispecific γδ T Cell Engager Containing Heterodimeric BTN2A1 and BTN3A1 Promotes Targeted Activation of Vγ9Vδ2⁺ T Cells in the Presence of Costimulation by CD28 or NKG2D

Cutting Edge: The Expression of Transcription Inhibitor GFI1 Is Induced by Retinoic Acid to Rein in Th9 Polarization

Cutting Edge: Systemic Autoimmunity in Murine STAT3 Gain-of-Function Syndrome Is Characterized by Effector T Cell Expansion in the Absence of Overt Regulatory T Cell Dysfunction

Cutting Edge: Hyperinflammatory Monocytes Expressing CD56 Abound in Severe COVID-19 Patients

Cutting Edge: Promoting T Cell Factor 1⁺ T Cell Self-Renewal to Improve Programmed Cell Death Protein 1 Blockade

Cutting Edge: T Cell Responses to B.1.1.529 (Omicron) SARS-CoV-2 Variant Induced by COVID-19 Infection and/or mRNA Vaccination Are Largely Preserved

Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil

Cutting Edge: Unconventional CD8⁺ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope

Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice

Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine–Induced Immune Responses in Multiple Sclerosis Patients

Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4⁺ T Cells following BNT162b2 Vaccination in the Elderly

Cutting Edge: l-Arginine Transfer from Antigen-Presenting Cells Sustains CD4⁺ T Cell Viability and Proliferation

Cutting Edge: Subunit Booster Vaccination Confers Sterilizing Immunity against Liver-Stage Malaria in Mice Initially Primed with a Weight-Normalized Dose of Radiation-Attenuated Sporozoites

Cutting Edge: DOCK8 Regulates a Subset of Dendritic Cells That Is Critical for the Development of Experimental Autoimmune Encephalomyelitis

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