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Cytokine and T Cell-Based Therapies 1
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Journal Articles

The effect of SMAC mimetics on human T cell activation

Susan E Murray, Brittany Ligman, Ashley Burton, Claire Kearney
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.13.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.13
Published: 01 May 2020
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The IL-15 receptor agonist N-803 combined with the anti-CD20 monoclonal antibody rituximab expands NK and CD8 T cells and alters single cell immune transcriptomes in a phase 1 clinical trial in lymphoma

Jennifer Ann Foltz-Stringfellow, Nancy L. Bartlett, Ethan McClain, Michelle Becker-Hapak, Brian T. Hess, Veronika Bachanova, Melissa M. Berrien-Elliott, Mark Foster, Timothy Schappe, Brad Kahl, Neha Mehta-Shah, Amanda F. Cashen, Kristin McDaniels, Chaz Moreno, Feng Gao, Obi Griffith, Malachi Griffith, Julia A. Wagner, Amy D. Rock, Patrick Soon-Shiong, John Lee, Allegra A. Petti, Todd A Fehniger
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.7.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.7
Published: 01 May 2020
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T helper differentiation of CAR T cells augments function and target cell killing

Andrew Scott Nelson, Ibrahim Khan, Mark H Kaplan
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.6.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.6
Published: 01 May 2020
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A single administration of Fc-fused recombinant human IL-7 induces expansions of T lymphocytes in healthy adults and cancer patients

Sojeong Kim, Minkyu Heo, Sohee Jeong, Jungwon Woo, Young Chul Sung, Eui-Cheol Shin, Su-Hyung Park
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.25.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.25
Published: 01 May 2020
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Harnessing antiviral memory T cells for tumor immunotherapy

Pamela Rosato, Sathi P Wijeyesinghe, Jianfang Ning, Noah Veis Gavil, Shaoping Wu, Clark Chen, Vaiva Vezys, David Masopust
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.24.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.24
Published: 01 May 2020
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Efficacy of agonist αOX40 and antagonist αCTLA-4 cancer immunotherapy is increased by ibrutinib treatment through enhanced Eomes expression and T-cell response

Dana A Emerson, William L Redmond
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.12.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.12
Published: 01 May 2020
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Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses

Hiroshi Nakashima, Quazim Alayo, E. Antonio Chiocca
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.11.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.11
Published: 01 May 2020
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Photo-regulated control of cytokine signaling via bioinspired, polymer-induced latency

Erik C Dreaden, Lacey A. Perdue, Priscilla Do, Andy Chyong, Khalid Salaita, Gregory Lesinski, Christopher C Porter
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.10.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.10
Published: 01 May 2020
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PD1 blockade augments adoptive T cell therapy via endogenous T cells rather than direct enhancement of transferred T cells

John S Davies, Farrah Karimipour, Ling Zhang, Carylinda Serna, Christian Hinrichs
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.1.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.1
Published: 01 May 2020
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Cytokine driven effector functions of CD8 cells: application to protease-activated cytokine therapy for cancer

Karli Norville, Denise Skrombolas, Shannon Ferry, Nancy Corson, John G. Frelinger
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.9.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.9
Published: 01 May 2020
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Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in solid tumors

Kristin G Anderson, Shannon K Oda, Breanna M Bates, Edison Y Chiu, Madison G Burnett, Magdalia L Suarez Gutierrez, Nicolas M Garcia, Andrew W Daman, Philip D Greenberg
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.8.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.8
Published: 01 May 2020
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Modulation of thymic architecture and T cell function by Mesenchymal stromal cell extracellular vesicles in a model of neonatal hyperoxia

Monica Reis, Gareth R. Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, Xianlan Liu, S. Alex Mitsialis, Stella Kourembanas
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.19.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.19
Published: 01 May 2020
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T cells exhibit prolonged immunity against melanoma tumors expressing high, but not low affinity antigens

Amalia M Rivera Reyes, Megan M. Wyatt, Connor J. Dwyer, Hannah M. Knochelmann, Aubrey S Smith, Guillermo O Rangel Rivera, Chrystal M Paulos
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.18.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.18
Published: 01 May 2020
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De novo DNA methylation programs regulate CAR T-cell exhaustion

Caitlin C Zebley, Christopher T. Petersen, Brooke Prinzing, Matthew Bell, Yiping Fan, Jeremy Chase Crawford, Haley Houke, Dalia Haydar, Zhongzhen Yi, Phuong Nguyen, Christopher DeRenzo, Cicera Lazzarotto, Shengdar Tsai, Shondra Miller, Deanna Langfitt, Stephen Gottschalk, Giedre Krenciute, Benjamin Youngblood
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.5.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.5
Published: 01 May 2020
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IL-6 fuels durable memory for Th17 cell-mediated responses to tumors

Hannah Knochelmann, Connor Dwyer, Aubrey S Smith, Megan Wyatt, Guillermo Rangel Rivera, Gregory Lesinski, Zihai Li, Mark Rubinstein, Chrystal M Paulos
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.4.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.4
Published: 01 May 2020
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Querying resources in the tumor microenvironment using bystander memory T cells

Surojit Sarkar, Peter Sullivan, Yevgeniy Yuzefpolskiy, Vandana Kalia
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.27.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.27
Published: 01 May 2020
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Phenotypic small-molecule screening identifies JAK inhibitors as pharmacologic modulators of T cell exhaustion

Brett S. Marro, Jaroslav Zak, Isaraphorn Pratumchai, Luke Lairson, Michael B.A. Oldstone, John R Teijaro
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.26.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.26
Published: 01 May 2020
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From biTEs to a novel switchable chimeric antigen receptor platform for gated tumor targeting

Michael P Bachmann, Nicole Berndt, Claudia Arndt, Anja Hoffmann, Stefanie Koristka, Liliana Loureiro, Anja Feldmann
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.31.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.31
Published: 01 May 2020
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Bispecific CAR T cells for multiple myeloma: natural ligand compared to tandem scFv design

Rebecca Larson, Ana Castano, Amanda Bouffard, Irene Scarfo, Michael Kann, Andrea Schmidts, Kathleen Gallagher, Marcela Valderrama Maus
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.3.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.3
Published: 01 May 2020
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Targeting microbial-specific gamma/delta T-cell subset for vaccine development

Zheng Chen, Ling Shen
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.29.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.246.29
Published: 01 May 2020
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