Tissue distribution of rat SIRP
| Tissue . | Cell . | Staining Intensity . |
|---|---|---|
| Spleen | Red pulp Mφ | +++a |
| Marginal zone Mφ | + | |
| Methalophilic Mφ | + | |
| Tingible body Mφ | − | |
| White pulp Mφ/DCb | + | |
| Isolated DC | +c | |
| Lymph node | Medullary Mφ | ++ |
| Subcapsular sinus Mφ | ++ | |
| Tingible body Mφ | − | |
| Paracortical Mφ/DC | + | |
| Peyer’s patches | Interfollicular Mφ/DC | ++ |
| Tingible body Mφ | − | |
| Thymus | Cortical Mφ | + |
| Corticomedullary Mφ/DC | + | |
| Medullary Mφ | − | |
| Bone marrow | Bone marrow Mφ | ++ |
| Hemopoietic cells | +d | |
| Liver | Kupffer cells | + |
| Lung | Alveolar Mφ | +++ |
| Interstitial Mφ | − | |
| Kidney | Glomerular Mφ | ++ |
| Interstitial Mφ | + | |
| Skin | Langerhans cells | ++e |
| Brain | Diffuse stainingf |
| Tissue . | Cell . | Staining Intensity . |
|---|---|---|
| Spleen | Red pulp Mφ | +++a |
| Marginal zone Mφ | + | |
| Methalophilic Mφ | + | |
| Tingible body Mφ | − | |
| White pulp Mφ/DCb | + | |
| Isolated DC | +c | |
| Lymph node | Medullary Mφ | ++ |
| Subcapsular sinus Mφ | ++ | |
| Tingible body Mφ | − | |
| Paracortical Mφ/DC | + | |
| Peyer’s patches | Interfollicular Mφ/DC | ++ |
| Tingible body Mφ | − | |
| Thymus | Cortical Mφ | + |
| Corticomedullary Mφ/DC | + | |
| Medullary Mφ | − | |
| Bone marrow | Bone marrow Mφ | ++ |
| Hemopoietic cells | +d | |
| Liver | Kupffer cells | + |
| Lung | Alveolar Mφ | +++ |
| Interstitial Mφ | − | |
| Kidney | Glomerular Mφ | ++ |
| Interstitial Mφ | + | |
| Skin | Langerhans cells | ++e |
| Brain | Diffuse stainingf |
+++, Strong staining; ++, moderate staining; +, weak staining; −, no staining.
Indicating dendritic cells and/or macrophages.
As determined after isolation of cells.
As determined in bone marrow suspensions (50–70% positive).
As confirmed by staining of epidermal sheets.
See text for details on cultured neurons and glial cells.