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Table II.

Tissue distribution of rat SIRP

TissueCellStaining Intensity
Spleen Red pulp Mφ +++a 
 Marginal zone Mφ 
 Methalophilic Mφ 
 Tingible body Mφ − 
 White pulp Mφ/DCb 
 Isolated DC +c 
Lymph node Medullary Mφ ++ 
 Subcapsular sinus Mφ ++ 
 Tingible body Mφ − 
 Paracortical Mφ/DC 
Peyer’s patches Interfollicular Mφ/DC ++ 
 Tingible body Mφ − 
Thymus Cortical Mφ 
 Corticomedullary Mφ/DC 
 Medullary Mφ − 
Bone marrow Bone marrow Mφ ++ 
 Hemopoietic cells +d 
Liver Kupffer cells 
Lung Alveolar Mφ +++ 
 Interstitial Mφ − 
Kidney Glomerular Mφ ++ 
 Interstitial Mφ 
Skin Langerhans cells ++e 
Brain  Diffuse stainingf 
TissueCellStaining Intensity
Spleen Red pulp Mφ +++a 
 Marginal zone Mφ 
 Methalophilic Mφ 
 Tingible body Mφ − 
 White pulp Mφ/DCb 
 Isolated DC +c 
Lymph node Medullary Mφ ++ 
 Subcapsular sinus Mφ ++ 
 Tingible body Mφ − 
 Paracortical Mφ/DC 
Peyer’s patches Interfollicular Mφ/DC ++ 
 Tingible body Mφ − 
Thymus Cortical Mφ 
 Corticomedullary Mφ/DC 
 Medullary Mφ − 
Bone marrow Bone marrow Mφ ++ 
 Hemopoietic cells +d 
Liver Kupffer cells 
Lung Alveolar Mφ +++ 
 Interstitial Mφ − 
Kidney Glomerular Mφ ++ 
 Interstitial Mφ 
Skin Langerhans cells ++e 
Brain  Diffuse stainingf 
a

+++, Strong staining; ++, moderate staining; +, weak staining; −, no staining.

b

Indicating dendritic cells and/or macrophages.

c

As determined after isolation of cells.

d

As determined in bone marrow suspensions (50–70% positive).

e

As confirmed by staining of epidermal sheets.

f

See text for details on cultured neurons and glial cells.

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