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Table III.

Homing of CD8low cells to sites of inflammation: IFN-γ production by CD8low cells in inflamed earsa

Phenotype of CD8+ T Cells% of Total CD8+ T Cellsb
CD8lowIFN-γ+ 31 
CD8lowIFN-γ 24 
CD8highIFN-γ+ 18 
CD8highIFN-γ 27 
Phenotype of CD8+ T Cells% of Total CD8+ T Cellsb
CD8lowIFN-γ+ 31 
CD8lowIFN-γ 24 
CD8highIFN-γ+ 18 
CD8highIFN-γ 27 
a

Sections of oxazolone-inflamed ears were prepared and stained for two-color immunohistochemistry as described in Materials and Methods. Control staining with normal rat IgG and without primary Abs demonstrated the specificity of the staining patterns and indicated that no cross-reactivity between color reactions developed.

b

Percentages represent the fraction of total CD8+ T cells that each subset comprises and were counted from >120 ×40 sections using one to two Tg mice in each of three independent experiments.

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