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Table III.

Effect of anti-integrin mAbs on viability of eosinophils incubated with soluble cellular fibronectina

AdditionsViability of Eosinophils on Day 3 (% of total)
Expt. 1Expt. 2Expt. 3Expt. 4Expt. 5
No addition 13 13 34 
Cellular fibronectin 37 38 34 40 60 
Cellular fibronectin+ anti-α1 mAb P4C10 30 24 39 41 57 
Cellular fibronectin+ anti-α4 mAb P4C2 32 27 34 ND ND 
Cellular fibronectin+ anti-β1 mAb P4C10+ anti-α4 mAb P4C2 ND 24 28 ND ND 
Cellular fibronectin+ anti-α4 mAb HP2/4 ND ND ND 35 69 
AdditionsViability of Eosinophils on Day 3 (% of total)
Expt. 1Expt. 2Expt. 3Expt. 4Expt. 5
No addition 13 13 34 
Cellular fibronectin 37 38 34 40 60 
Cellular fibronectin+ anti-α1 mAb P4C10 30 24 39 41 57 
Cellular fibronectin+ anti-α4 mAb P4C2 32 27 34 ND ND 
Cellular fibronectin+ anti-β1 mAb P4C10+ anti-α4 mAb P4C2 ND 24 28 ND ND 
Cellular fibronectin+ anti-α4 mAb HP2/4 ND ND ND 35 69 
a

Data are shown as the mean of three wells of each experiment.

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