Components and doses of vaccination in the rhIL-12 dose ranging experiment (Expt. 1) and in the HKLV/alum dose ranging experiment (Expt. 2)
| Expt.a . | Components and Doses . |
|---|---|
| 1a | Saline |
| 1b | Alum (0.5 mg)+ rhIL-12 (1 μg) |
| 1c | HKLV (1 mg) |
| 1d | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (0.04 μg) |
| 1e | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (0.2 μg) |
| 1f | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (1 μg) |
| 2a | Saline |
| 2b | HKLV (1 mg)+ rhIL-12 (2 μg) |
| 2c | HKLV (1 mg)+ alum (0.5 mg) |
| 2d | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (2 μg) |
| 2e | HKLV (0.5 mg)+ alum (0.25 mg)+ rhIL-12 (2 μg) |
| 2f | HKLV (0.25 mg)+ alum (0.125 mg)+ rhIL-12 (2 μg) |
| Expt.a . | Components and Doses . |
|---|---|
| 1a | Saline |
| 1b | Alum (0.5 mg)+ rhIL-12 (1 μg) |
| 1c | HKLV (1 mg) |
| 1d | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (0.04 μg) |
| 1e | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (0.2 μg) |
| 1f | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (1 μg) |
| 2a | Saline |
| 2b | HKLV (1 mg)+ rhIL-12 (2 μg) |
| 2c | HKLV (1 mg)+ alum (0.5 mg) |
| 2d | HKLV (1 mg)+ alum (0.5 mg)+ rhIL-12 (2 μg) |
| 2e | HKLV (0.5 mg)+ alum (0.25 mg)+ rhIL-12 (2 μg) |
| 2f | HKLV (0.25 mg)+ alum (0.125 mg)+ rhIL-12 (2 μg) |
Four macaques in each group were injected once s.c. in the arm with the indicated components diluted to 0.5 ml with PBS.