Peptides used for competition assays to determine SLP-76/SH3 interaction sitesa
| Peptide . | Corresponding to Amino Acids . | Amino Acid Sequence . |
|---|---|---|
| SLP-76 peptides | ||
| A | 488–497 | G L R G K E D F L S |
| B | 84–93 | R K P Q V P R F P E |
| C | 143–152 | A D Y E P P P S N D |
| D | 182–191 | T P Q Q P P V P P Q |
| E | 185–194 | Q P P V P P Q R P M |
| F | 195–204 | A A L P P P P A G R |
| G | 206–215 | H S P L P P P Q T N |
| H | 283–292 | Q K P P L P P T T E |
| I | 348–357 | K P S P M N P L P S |
| K | 400–411 | L P L P N K P R P P S P |
| c-Cbl peptides | ||
| L | 542–551 | L P P P P P P D R P |
| M | 489–498 | P Q A S L P P V P P |
| Peptide . | Corresponding to Amino Acids . | Amino Acid Sequence . |
|---|---|---|
| SLP-76 peptides | ||
| A | 488–497 | G L R G K E D F L S |
| B | 84–93 | R K P Q V P R F P E |
| C | 143–152 | A D Y E P P P S N D |
| D | 182–191 | T P Q Q P P V P P Q |
| E | 185–194 | Q P P V P P Q R P M |
| F | 195–204 | A A L P P P P A G R |
| G | 206–215 | H S P L P P P Q T N |
| H | 283–292 | Q K P P L P P T T E |
| I | 348–357 | K P S P M N P L P S |
| K | 400–411 | L P L P N K P R P P S P |
| c-Cbl peptides | ||
| L | 542–551 | L P P P P P P D R P |
| M | 489–498 | P Q A S L P P V P P |
Proline residues characteristic for potential SH3 binding sites are highlighted in bold.