Table I.

Arterial blood gas analyses

ParameterEarly Phase (24 h)Late Phase (60 h)
ControlCLP + preimmune IgGCLP + anti-C5aControlCLP + preimmune IgGCLP + anti-C5a
pH 7.47 ± 0.01 7.53 ± 0.01* 7.49 ± 0.01 7.48 ± .003 7.34 ± .008* 7.49 ± .003 
pCO2 (mmHg) 38.6 ± 0.89 34.2 ± 0.91* 37.2 ± 0.62 36.6 ± 1.29 44.5 ± 3.32 37.9 ± 2.34 
HCO3 (mmol/L) 26.4 ± 1.14 26.9 ± 0.50 28.1 ± 0.76 26.6 ± 0.47 20.8 ± 1.86* 26.4 ± 1.14 
pO2 (mmHg) 106 ± 0.88 106.4 ± 7.86 112.5 ± 2.50 105 ± 0.88 69.8 ± 9.79* 106 ± 4.17 
ParameterEarly Phase (24 h)Late Phase (60 h)
ControlCLP + preimmune IgGCLP + anti-C5aControlCLP + preimmune IgGCLP + anti-C5a
pH 7.47 ± 0.01 7.53 ± 0.01* 7.49 ± 0.01 7.48 ± .003 7.34 ± .008* 7.49 ± .003 
pCO2 (mmHg) 38.6 ± 0.89 34.2 ± 0.91* 37.2 ± 0.62 36.6 ± 1.29 44.5 ± 3.32 37.9 ± 2.34 
HCO3 (mmol/L) 26.4 ± 1.14 26.9 ± 0.50 28.1 ± 0.76 26.6 ± 0.47 20.8 ± 1.86* 26.4 ± 1.14 
pO2 (mmHg) 106 ± 0.88 106.4 ± 7.86 112.5 ± 2.50 105 ± 0.88 69.8 ± 9.79* 106 ± 4.17 
a

, Significant difference (p < 0.05) vs effects of anti-C5a treatment.

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