Table III.

The proportion of CD8+/tetramer+ or CD8+/tetramer cells expressing the indicated markers after resolution of A/HKx31 influenza virus infectiona

TissueCD8+/tetramer+CD8+/tetramer–
CD44+CD69+CD25+CD43+*CD44+CD69+CD25+CD43+*
BAL 97 70 82 71 97 51 74 
Lung 94 47 88 44 44 11 
MLN 96 34 91 65 17 
Spleen 93 27 81 58 29 
TissueCD8+/tetramer+CD8+/tetramer–
CD44+CD69+CD25+CD43+*CD44+CD69+CD25+CD43+*
BAL 97 70 82 71 97 51 74 
Lung 94 47 88 44 44 11 
MLN 96 34 91 65 17 
Spleen 93 27 81 58 29 
a

C57BL/6 mice were intranasally infected with 300 EID50 A/HKx31 and analyzed 31 days or 46 days (*) postinfection. Cells were stained with influenza virus NP366–373/Db MHC tetramers, anti-CD8 mAb, and mAb specific for the indicated markers. The data are presented as the proportion of either tetramer+/CD8+ cells or tetramer/CD8+, which stained positive for the markers listed above.

Close Modal

or Create an Account

Close Modal
Close Modal