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Table I.

HCC patient characteristics

Patient CodeAge/SexNumber of Tumor Lesions, SizeHistologyaSerologyHLA-A, -Bb
LAU 669 70/male Six lesions, diameters 18, 5.5, 2, 1.8, 1.6, and 0.8 cm; infiltration of neighbouring organs Low differentiation; moderate lymphocytic infiltration HBs negative, anti-HBc negative, HCV negative, anti-HCV negative A*0201, A24(9), B62(15), Bx 
LAU 674 68/male Three lesions, largest lesion 3 × 2 × 2 cm Moderate differentiation; slight lymphocytic inifiltration; liver cirrhosis. HBs negative, anti-HBc negative, anti-HCV positive A*0201c, A3, B35, B51(5) 
LAU 698 75/male Two lesions, diameters 5 and 3.5 cm Moderate differentiation; slight lymphocytic infiltration HBs negative, anti-HBc negative, HCV negative, anti-HCV negative A1, A*0201, B7, B37 
LAU 748 81/female One lesion, diameter 13 × 6 × 5 cm Low differentiation; no lymphocytic infiltration HBs negative, anti-HBc negative, anti-HCV negative A*0201, A28, B18, B27 
LAU 766 70/male Multiple lesions, diameters between 1 and 2 cm Moderate differentiation; no lymphocytic infiltration; liver cirrhosis HBs negative, anti-HBc negative, anti-HCV positive A*0201, A*31d 
LAU 812 68/female One lesion, diameter 2 × 2 × 2 cm Well differentiated; strong lymphocytic infiltration HBs negative, anti-HBc negative, anti-HCV negative A*0201, A3, B13, B62(15) 
Patient CodeAge/SexNumber of Tumor Lesions, SizeHistologyaSerologyHLA-A, -Bb
LAU 669 70/male Six lesions, diameters 18, 5.5, 2, 1.8, 1.6, and 0.8 cm; infiltration of neighbouring organs Low differentiation; moderate lymphocytic infiltration HBs negative, anti-HBc negative, HCV negative, anti-HCV negative A*0201, A24(9), B62(15), Bx 
LAU 674 68/male Three lesions, largest lesion 3 × 2 × 2 cm Moderate differentiation; slight lymphocytic inifiltration; liver cirrhosis. HBs negative, anti-HBc negative, anti-HCV positive A*0201c, A3, B35, B51(5) 
LAU 698 75/male Two lesions, diameters 5 and 3.5 cm Moderate differentiation; slight lymphocytic infiltration HBs negative, anti-HBc negative, HCV negative, anti-HCV negative A1, A*0201, B7, B37 
LAU 748 81/female One lesion, diameter 13 × 6 × 5 cm Low differentiation; no lymphocytic infiltration HBs negative, anti-HBc negative, anti-HCV negative A*0201, A28, B18, B27 
LAU 766 70/male Multiple lesions, diameters between 1 and 2 cm Moderate differentiation; no lymphocytic infiltration; liver cirrhosis HBs negative, anti-HBc negative, anti-HCV positive A*0201, A*31d 
LAU 812 68/female One lesion, diameter 2 × 2 × 2 cm Well differentiated; strong lymphocytic infiltration HBs negative, anti-HBc negative, anti-HCV negative A*0201, A3, B13, B62(15) 
a

Tumor differentiation and cirrhosis was analyzed with H&E sections. Intratumoral T cell infiltration was analyzed with sections stained with CD3-specific Ab.

b

HLA typing for HLA-A,-B was done by serology, and for A2 subtypes with HLA allele-sequence-specific primers.

c

The rare alleles A*0259/60/64 cannot be excluded.

d

The rare heterozygous combinations A*0258/59/60/64 and A*3109 cannot be excluded.

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