TLR expression in other cell types present in human intestine
TLRs . | LP Macrophages . | Dendritic Cells . | Myofibroblast . | Endothelial Cells . | Circulating PMNs . |
---|---|---|---|---|---|
1 | Not expressed (18 ) | ND | + RNA, protein (95 ) | ND | + RNA (96 ), + protein (97 98 ) |
2 | + RNA, low expression; Increased in IBD (18 ) | ND | +* (95 ) | ND | +* RNA (96 ), + protein (97 ), + function (99 ) |
3 | Not expressed (18 ) | + Inferred expression (54 ) | + RNA, protein (95 ) | ND | Not expressed (96 ), + function (99 ) |
4 (MD2) | + RNA, low expression; Increased in IBD (18 100 ) | + Inferred expression (54 ) | +* (95 ) | + Functional (101 ) | +* RNA (96 ), + protein (97 ), + function (99 ) |
5 | + RNA (in IBD) (18 ) | ND | + RNA, protein (95 ) | + functional (102 ) | + RNA (96 ), negative function (99 ) |
6 | ND | ND | + RNA, protein (95 ) | ND | + RNA (98 ) |
7 | ND | ND | + RNA, protein (95 ) | ND | + Functional (103 ) (99 ) |
8 | ND | ND | + RNA, protein (95 ) | ND | + Functional (99 ) |
9 | ND | ND | + (95 ) CCD-18 cells | ND | + RNA (99 ) |
10 | ND | ND | − (Not expressed) (95 ) | ND | + RNA (99 ) |
TLRs . | LP Macrophages . | Dendritic Cells . | Myofibroblast . | Endothelial Cells . | Circulating PMNs . |
---|---|---|---|---|---|
1 | Not expressed (18 ) | ND | + RNA, protein (95 ) | ND | + RNA (96 ), + protein (97 98 ) |
2 | + RNA, low expression; Increased in IBD (18 ) | ND | +* (95 ) | ND | +* RNA (96 ), + protein (97 ), + function (99 ) |
3 | Not expressed (18 ) | + Inferred expression (54 ) | + RNA, protein (95 ) | ND | Not expressed (96 ), + function (99 ) |
4 (MD2) | + RNA, low expression; Increased in IBD (18 100 ) | + Inferred expression (54 ) | +* (95 ) | + Functional (101 ) | +* RNA (96 ), + protein (97 ), + function (99 ) |
5 | + RNA (in IBD) (18 ) | ND | + RNA, protein (95 ) | + functional (102 ) | + RNA (96 ), negative function (99 ) |
6 | ND | ND | + RNA, protein (95 ) | ND | + RNA (98 ) |
7 | ND | ND | + RNA, protein (95 ) | ND | + Functional (103 ) (99 ) |
8 | ND | ND | + RNA, protein (95 ) | ND | + Functional (99 ) |
9 | ND | ND | + (95 ) CCD-18 cells | ND | + RNA (99 ) |
10 | ND | ND | − (Not expressed) (95 ) | ND | + RNA (99 ) |