The effect of spermine on the expression of adhesion molecules in the lymphocyte regiona
| . | Spermine Concentration (μM) . | . | . | ||
|---|---|---|---|---|---|
| . | 0 . | 100 . | 500 . | ||
| MFI | |||||
| CD11a (n = 12) | 50.7 ± 3.3 | 49.0 ± 3.3b | 46.1 ± 3.2bc | ||
| CD11b (n = 9) | 26.0 ± 2.6 | 25.2 ± 2.2 | 26.2 ± 2.3 | ||
| CD11c (n = 9) | 19.6 ± 1.7 | 20.3 ± 1.9 | 19.7 ± 1.8 | ||
| CD18 (n = 6) | 18.8 ± 2.9 | 17.5 ± 3.0 | 16.8 ± 2.8b | ||
| CD31 (n = 6) | 54.1 ± 4.7 | 53.9 ± 4.4 | 52.4 ± 3.9 | ||
| CD49d (n = 6) | 114.8 ± 7.2 | 118.6 ± 6.7 | 119.5 ± 8.2 | ||
| CD49e (n = 6) | 45.2 ± 1.0 | 45.0 ± 1.8 | 45.7 ± 1.5 | ||
| CD54 (n = 6) | 35.2 ± 7.3 | 35.1 ± 7.2 | 35.0 ± 7.8 | ||
| Percentage of expressing cells | |||||
| CD11a (n = 12) | 94.7 ± 2.5 | 95.0 ± 2.5 | 94.9 ± 2.7 | ||
| CD11b (n = 9) | 6.1 ± 0.9 | 5.8 ± 1.0 | 6.4 ± 1.1 | ||
| CD11c (n = 9) | 4.1 ± 0.6 | 3.9 ± 0.5 | 3.9 ± 0.5 | ||
| CD18 (n = 6) | 93.4 ± 2.2 | 90.7 ± 2.4 | 90.9 ± 2.4 | ||
| CD31 (n = 6) | 46.2 ± 6.6 | 45.5 ± 6.7 | 45.1 ± 6.5b | ||
| CD49d (n = 6) | 93.5 ± 1.0 | 93.6 ± 1.0 | 93.7 ± 1.0 | ||
| CD49e (n = 6) | 87.3 ± 2.7 | 86.3 ± 2.9 | 86.0 ± 2.9b | ||
| CD54 (n = 6) | 76.3 ± 6.3 | 77.8 ± 6.5 | 77.1 ± 6.9 | ||
| . | Spermine Concentration (μM) . | . | . | ||
|---|---|---|---|---|---|
| . | 0 . | 100 . | 500 . | ||
| MFI | |||||
| CD11a (n = 12) | 50.7 ± 3.3 | 49.0 ± 3.3b | 46.1 ± 3.2bc | ||
| CD11b (n = 9) | 26.0 ± 2.6 | 25.2 ± 2.2 | 26.2 ± 2.3 | ||
| CD11c (n = 9) | 19.6 ± 1.7 | 20.3 ± 1.9 | 19.7 ± 1.8 | ||
| CD18 (n = 6) | 18.8 ± 2.9 | 17.5 ± 3.0 | 16.8 ± 2.8b | ||
| CD31 (n = 6) | 54.1 ± 4.7 | 53.9 ± 4.4 | 52.4 ± 3.9 | ||
| CD49d (n = 6) | 114.8 ± 7.2 | 118.6 ± 6.7 | 119.5 ± 8.2 | ||
| CD49e (n = 6) | 45.2 ± 1.0 | 45.0 ± 1.8 | 45.7 ± 1.5 | ||
| CD54 (n = 6) | 35.2 ± 7.3 | 35.1 ± 7.2 | 35.0 ± 7.8 | ||
| Percentage of expressing cells | |||||
| CD11a (n = 12) | 94.7 ± 2.5 | 95.0 ± 2.5 | 94.9 ± 2.7 | ||
| CD11b (n = 9) | 6.1 ± 0.9 | 5.8 ± 1.0 | 6.4 ± 1.1 | ||
| CD11c (n = 9) | 4.1 ± 0.6 | 3.9 ± 0.5 | 3.9 ± 0.5 | ||
| CD18 (n = 6) | 93.4 ± 2.2 | 90.7 ± 2.4 | 90.9 ± 2.4 | ||
| CD31 (n = 6) | 46.2 ± 6.6 | 45.5 ± 6.7 | 45.1 ± 6.5b | ||
| CD49d (n = 6) | 93.5 ± 1.0 | 93.6 ± 1.0 | 93.7 ± 1.0 | ||
| CD49e (n = 6) | 87.3 ± 2.7 | 86.3 ± 2.9 | 86.0 ± 2.9b | ||
| CD54 (n = 6) | 76.3 ± 6.3 | 77.8 ± 6.5 | 77.1 ± 6.9 | ||
Changes in MFI and in the percentage of cells expressing one of the membrane molecules on cells in the lymphocyte light-scattered region. Thirty to 50 thousand cells gated in the lymphocyte and monocyte light-scatter regions were counted. Data are presented as mean ± SE.
, p < 0.05 vs 0 μM;
, p < 0.05 vs 100 μM.