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Table I.

Thymocyte subset numbers following 1-wk treatment with 1 μg/μl plasmid control, IL-7, or fusion plasmid; showing averages and SD (n = 6)a

PopulationControl (±SD)IL-7 (±SD)Fusion (±SD)
CD44+CD25 (DN1) 0.81 ± 0.2 × 105 3.3 ± 0.1 × 105b 8.7 ± 0.3 × 105ce 
CD44+CD25+ (DN2) 0.82 ± 0.4 × 105 1.4 ± 0.5 × 105 2.2 ± 0.6 × 105b 
CD44CD25+ (DN3) 2.6 ± 0.9 × 105 3.5 ± 0.7 × 105 4.2 ± 1.2 × 105b 
CD44CD25 (DN4) 4.8 ± 5.5 × 105 6.8 ± 1.3 × 105 7.5 ± 1.8 × 105b 
    
CD4+CD8+ 18 ± 9.1 × 106 20 ± 2.9 × 106 25 ± 4 × 106 
CD4+CD8 4.5 ± 1.3 × 106 6.7 ± 1.1 × 106b 8.3 ± 0.8 × 106bd 
CD4CD8+ 2.3 ± 0.6 × 106 2.6 ± 0.5 × 106 3.1 ± 0.1 × 106 
PopulationControl (±SD)IL-7 (±SD)Fusion (±SD)
CD44+CD25 (DN1) 0.81 ± 0.2 × 105 3.3 ± 0.1 × 105b 8.7 ± 0.3 × 105ce 
CD44+CD25+ (DN2) 0.82 ± 0.4 × 105 1.4 ± 0.5 × 105 2.2 ± 0.6 × 105b 
CD44CD25+ (DN3) 2.6 ± 0.9 × 105 3.5 ± 0.7 × 105 4.2 ± 1.2 × 105b 
CD44CD25 (DN4) 4.8 ± 5.5 × 105 6.8 ± 1.3 × 105 7.5 ± 1.8 × 105b 
    
CD4+CD8+ 18 ± 9.1 × 106 20 ± 2.9 × 106 25 ± 4 × 106 
CD4+CD8 4.5 ± 1.3 × 106 6.7 ± 1.1 × 106b 8.3 ± 0.8 × 106bd 
CD4CD8+ 2.3 ± 0.6 × 106 2.6 ± 0.5 × 106 3.1 ± 0.1 × 106 
a

Denotes significant difference when compared with the control animals:

b

, p < 0.01;

c

, p < 0.001. Denotes significant difference between IL-7- and fusion-treated animals:

d

, p < 0.05;

e

, p < 0.001.

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