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Table I.

Three independent T cell phenotypes

GenotypeLymphoid MHC Class ISplenic CD4:CD8T Cell Proliferation
MECL-1−/− LMP7−/− ↓ ↑ ↑ 
MECL-1−/− Normal ↑ Normal 
LMP7−/− ↓ Normal Normal 
LMP2−/− Normal ↑ Normal 
GenotypeLymphoid MHC Class ISplenic CD4:CD8T Cell Proliferation
MECL-1−/− LMP7−/− ↓ ↑ ↑ 
MECL-1−/− Normal ↑ Normal 
LMP7−/− ↓ Normal Normal 
LMP2−/− Normal ↑ Normal 
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