Clinical impact of treatment
| Groups . | Pocket Depth (mm)ab . | . | Infrabony Defect Depth (mm) . | . | Tooth Mobilityc . | ||
|---|---|---|---|---|---|---|---|
| . | Buccal . | Lingual . | Buccal . | Lingual . | . | ||
| Baseline periodontitis | 3.9 ± 1.1 | 3.2 ± 1.0 | 4.2 ± 0.9 | 3.6 ± 1.0 | 0.8 ± 0.4 | ||
| Vehicle-alone | 7.0 ± 0.8d | 6.1 ± 0.7d | 6.9 ± 0.7d | 6.0 ± 0.6d | 2.6 ± 0.3d | ||
| RvE1-treated | 0.7 ± 0.8e | 0.4 ± 0.7e | 0.6 ± 0.3e | 0.6 ± 0.3e | 0.2 ± 0.3e | ||
| LTB4-treated | 5.1 ± 0.4d | 4.5 ± 0.4d | 5.2 ± 0.8d | 4.3 ± 0.3 | 1.9 ± 0.4d | ||
| PGE2-treated | 6.6 ± 0.4d | 5.9 ± 0.7d | 7.2 ± 0.4d | 6.4 ± 0.7d | 2.8 ± 0.3d | ||
| Groups . | Pocket Depth (mm)ab . | . | Infrabony Defect Depth (mm) . | . | Tooth Mobilityc . | ||
|---|---|---|---|---|---|---|---|
| . | Buccal . | Lingual . | Buccal . | Lingual . | . | ||
| Baseline periodontitis | 3.9 ± 1.1 | 3.2 ± 1.0 | 4.2 ± 0.9 | 3.6 ± 1.0 | 0.8 ± 0.4 | ||
| Vehicle-alone | 7.0 ± 0.8d | 6.1 ± 0.7d | 6.9 ± 0.7d | 6.0 ± 0.6d | 2.6 ± 0.3d | ||
| RvE1-treated | 0.7 ± 0.8e | 0.4 ± 0.7e | 0.6 ± 0.3e | 0.6 ± 0.3e | 0.2 ± 0.3e | ||
| LTB4-treated | 5.1 ± 0.4d | 4.5 ± 0.4d | 5.2 ± 0.8d | 4.3 ± 0.3 | 1.9 ± 0.4d | ||
| PGE2-treated | 6.6 ± 0.4d | 5.9 ± 0.7d | 7.2 ± 0.4d | 6.4 ± 0.7d | 2.8 ± 0.3d | ||
Distance between tip of the gingiva and soft tissue attachment on the tooth surface.
Vertical dimension of bone loss (distance between the tip of the tooth and the base of the bone defect).
Movement of the tooth as a result of bone and soft tissue attachment loss.
p < 0.05 compared with baseline periodontitis group.
p < 0.01 compared with baseline periodontitis, vehicle-alone, LTB4-, and PGE2-treated groups.