(Continued)
| Gene . | Description . | Fold Induction . | . | . | Ratiob . | ||
|---|---|---|---|---|---|---|---|
| . | . | TREM . | LPS . | Dual . | . | ||
| CCR7 | Chemokine (C-C motif) receptor 7 | 2.5 | 7.1 | 7.3 | 2.9 | ||
| UPB1 | Ureidopropionase, β; pyrimidine degradation | 1.3 | 4.9 | 3.1 | 2.8 | ||
| FJX1 | Four jointed box 1 (Drosophila) | 1.1 | 4.1 | 1.8 | 2.7 | ||
| MBNL1 | Muscleblind-like (Drosophila) | 1.5 | 4.0 | 2.7 | 2.7 | ||
| EREG | EGF family (epiregulin) | 2.0 | 5.0 | 3.7 | 2.7 | ||
| ID2 | Inhibitor of DNA binding 2; HLH containing | 1.7 | 4.8 | 3.7 | 2.5 | ||
| MGLL | Monoglyceride lipase | 1.6 | 5.4 | 4.1 | 2.5 | ||
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 2.9 | 6.2 | 6.1 | 2.4 | ||
| FLT1 | Fms-related tyrosine kinase 1; VEGF/VEGFA receptor | 3.4 | 9.4 | 7.1 | 2.3 | ||
| HEY1 | Hairy/enhancer-of-split related; bHLH containing | 2.4 | 5.4 | 5.0 | 2.3 | ||
| PIM3 | Pim-3 oncogene; serine/threonine kinase | 2.1 | 4.5 | 4.7 | 2.2 | ||
| TNFSF9 | TNF ligand superfamily, member 9 | 1.7 | 4.9 | 2.5 | 2.1 | ||
| Gene . | Description . | Fold Induction . | . | . | Ratiob . | ||
|---|---|---|---|---|---|---|---|
| . | . | TREM . | LPS . | Dual . | . | ||
| CCR7 | Chemokine (C-C motif) receptor 7 | 2.5 | 7.1 | 7.3 | 2.9 | ||
| UPB1 | Ureidopropionase, β; pyrimidine degradation | 1.3 | 4.9 | 3.1 | 2.8 | ||
| FJX1 | Four jointed box 1 (Drosophila) | 1.1 | 4.1 | 1.8 | 2.7 | ||
| MBNL1 | Muscleblind-like (Drosophila) | 1.5 | 4.0 | 2.7 | 2.7 | ||
| EREG | EGF family (epiregulin) | 2.0 | 5.0 | 3.7 | 2.7 | ||
| ID2 | Inhibitor of DNA binding 2; HLH containing | 1.7 | 4.8 | 3.7 | 2.5 | ||
| MGLL | Monoglyceride lipase | 1.6 | 5.4 | 4.1 | 2.5 | ||
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 2.9 | 6.2 | 6.1 | 2.4 | ||
| FLT1 | Fms-related tyrosine kinase 1; VEGF/VEGFA receptor | 3.4 | 9.4 | 7.1 | 2.3 | ||
| HEY1 | Hairy/enhancer-of-split related; bHLH containing | 2.4 | 5.4 | 5.0 | 2.3 | ||
| PIM3 | Pim-3 oncogene; serine/threonine kinase | 2.1 | 4.5 | 4.7 | 2.2 | ||
| TNFSF9 | TNF ligand superfamily, member 9 | 1.7 | 4.9 | 2.5 | 2.1 | ||
Genes up-regulated >4-fold with LPS that are not commonly up-regulated. Shown are fold inductions with TREM-1 activation (column labeled “TREM”), LPS (column labeled “LPS”), TREM-1 activation plus LPS treatment (column labeled “Dual”), and the ratio of average expression in a direct pairwise comparison of LPS to TREM-1 activation (ratio). Genes are ranked by ratio, i.e., how biased their induction was towards LPS when compared to TREM-1 activation. p values for genes up-regulated >4-fold with LPS in this table ranged from 1.2 × 10−3 to 3.6 × 10−14. Genes that met the filtering criteria but are not listed are C10orf78, C21orf71, FLJ14490, FLJ23231, FLJ25590, FLJ32499, KIAA0286, KIAA0376, LOC90167, LOC123872, LOC285628, LOC338758, LOC341720, LOCLOC374443, LOC387763, LOC400581, LOC441366, MGC10744, and MGC11082.
LPS/TREM ratio from direct pairwise comparison.
TRGV9/TARP.