Table I.
Relative activity of DMF4 TCR with wt and different chimeric C regions
Mutant NameNo. of Amino Acid Difference with Ha/HbPercent Difference with Ha/HbPercent Relative Activity
Ha/Hb 0 0 14 
B-ULT/K2 9 3 32 
B-ULT/KA 10 3 52 
ULT/KA 20 6 61 
ULT/40b 29 9 72 
Ma/40b 53 16 89 
ULT/Mb 55 17 83 
Ma/Mb 80 25 100 
Mutant NameNo. of Amino Acid Difference with Ha/HbPercent Difference with Ha/HbPercent Relative Activity
Ha/Hb 0 0 14 
B-ULT/K2 9 3 32 
B-ULT/KA 10 3 52 
ULT/KA 20 6 61 
ULT/40b 29 9 72 
Ma/40b 53 16 89 
ULT/Mb 55 17 83 
Ma/Mb 80 25 100 
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