Table II.
Suppression of phosphorylated STAT3 in the peripheral blood of rAIA animals treated orally with INCB028050 (
n
= 3)
Dose (mg/kg)
.
% Inhibition at 1 h
.
% Inhibition at 4 h
.
% Inhibition at 24 h
.
1
55 ± 6
0.1 ± 37
0
3
100
13 ± 37
0
10
100
84 ± 18
0
Dose (mg/kg)
.
% Inhibition at 1 h
.
% Inhibition at 4 h
.
% Inhibition at 24 h
.
1
55 ± 6
0.1 ± 37
0
3
100
13 ± 37
0
10
100
84 ± 18
0
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