Table IV.
Oral administration of INCB028050 (10 mg/kg) reduces elevated cytokine mRNA levels in draining lymph nodes from rats with AIA
Expression Relative to Control (d 3)Expression Relative to Control (d 14)% Inhibition by INCB028050 (d 14)
IFN-γ 1.1 7.0 65 
IL-12a 2.1 4.4 76 
IL-17 1.6 244.7 55 
IL-21 1.3 4.5 75 
IL-22 8.3 330.1 79 
Expression Relative to Control (d 3)Expression Relative to Control (d 14)% Inhibition by INCB028050 (d 14)
IFN-γ 1.1 7.0 65 
IL-12a 2.1 4.4 76 
IL-17 1.6 244.7 55 
IL-21 1.3 4.5 75 
IL-22 8.3 330.1 79 
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