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Table I.

Vessel diameter in rats before (basal) and at different time points (15–60 min) after the addition of the PAR2-APs (SL-NH2 and Tc-NH2) or control peptides (LR-NH2 and LS-NH2)a

Time (min)Vessel Diameter (μm)
LR-NH2 (control)LS-NH2 (control)SL-NH2 (PAR2-AP)Tc-NH2 (PAR2-AP)
Basal 29.1 ± 2.9 31.2 ± 1.1 33.3 ± 2.1 29.0 ± 2.3 
15 29.7 ± 2.9 32.4 ± 0.8 33.0 ± 1.7 25.5 ± 2.8 
30 29.7 ± 2.9 33.5 ± 1.3 33.7 ± 2.4 27.3 ± 2.4 
45 29.5 ± 3.0 33.3 ± 1.5 33.4 ± 2.3 27.8 ± 2.1 
60 29.6 ± 2.6 32.2 ± 1.6 33.3 ± 2.4 28.8 ± 2.6 
Time (min)Vessel Diameter (μm)
LR-NH2 (control)LS-NH2 (control)SL-NH2 (PAR2-AP)Tc-NH2 (PAR2-AP)
Basal 29.1 ± 2.9 31.2 ± 1.1 33.3 ± 2.1 29.0 ± 2.3 
15 29.7 ± 2.9 32.4 ± 0.8 33.0 ± 1.7 25.5 ± 2.8 
30 29.7 ± 2.9 33.5 ± 1.3 33.7 ± 2.4 27.3 ± 2.4 
45 29.5 ± 3.0 33.3 ± 1.5 33.4 ± 2.3 27.8 ± 2.1 
60 29.6 ± 2.6 32.2 ± 1.6 33.3 ± 2.4 28.8 ± 2.6 
a

The tested peptides were superfused on the postcapillary mesenteric venules for 1 min. starting immediately after the basal period. Values are mean ± SEM of n = 6 per group.

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