| mAb . | Binding to . | Inhibition of SMAD3 phosphorylation . | Ref. . | ||
|---|---|---|---|---|---|
| L-TGF-β . | GARP . | L-TGF-β/GARP . | |||
| 28G11 | √ | X | √ | √ | (44) |
| AB2 | √ | X | √ | X | (45) |
| MHG-8 | X | X | √ | √ | (21) |
| LHG-10 | X | X | √ | √ | (21) |
| 105F | X | √ | √ | X | (46) |
| 110F | X | √ | √ | X | (46) |
| 5C5 | X | √ | √ | (√) | (47) |
| 3C9 | X | √ | √ | (√) | — |
| 15A3 | X | √ | √ | X | — |
| 21A11 | X | √ | √ | X | — |
| 12A2F8 | X | √ | √ | √ | — |
| 12B9H5 | X | √ | √ | √ | — |
| 12G2B4 | X | √ | √ | √ | — |
| 14G2D8 | X | √ | √ | X | — |
| 21A11B7 | X | √ | √ | X | — |
| 22H6H5 | X | √ | √ | X | — |
| mAb . | Binding to . | Inhibition of SMAD3 phosphorylation . | Ref. . | ||
|---|---|---|---|---|---|
| L-TGF-β . | GARP . | L-TGF-β/GARP . | |||
| 28G11 | √ | X | √ | √ | (44) |
| AB2 | √ | X | √ | X | (45) |
| MHG-8 | X | X | √ | √ | (21) |
| LHG-10 | X | X | √ | √ | (21) |
| 105F | X | √ | √ | X | (46) |
| 110F | X | √ | √ | X | (46) |
| 5C5 | X | √ | √ | (√) | (47) |
| 3C9 | X | √ | √ | (√) | — |
| 15A3 | X | √ | √ | X | — |
| 21A11 | X | √ | √ | X | — |
| 12A2F8 | X | √ | √ | √ | — |
| 12B9H5 | X | √ | √ | √ | — |
| 12G2B4 | X | √ | √ | √ | — |
| 14G2D8 | X | √ | √ | X | — |
| 21A11B7 | X | √ | √ | X | — |
| 22H6H5 | X | √ | √ | X | — |
√, binding or inhibiting, respectively; X, no binding or no inhibition, respectively; (√), partial inhibition; —, from internal campaign.