Adoptive transfer of intestinally derived CD4⁺ T cells from infected IL-10 KO mice induces hepatic inflammation in infected recipients whereas cells from infected WT mice are protective. A, Experimental design (n = 3 mice/group). B, ALT activity was measured. The checks indicate the groups of mice that developed gross hepatic lesions. The lines start and stop at groups that were statistically significantly different. C, Histological sections from representative animals. Arrows indicate periphery of the lesions. Bar, 100 μm. D, On day 12, livers were collected and processed for flow cytometry. The average number of CD4⁺α₄β₇⁺ cells per liver ± SD is shown. The lines start and stop at groups that were statistically significantly different.